SynthesisInternational journal of cardiology2017
Clinical applications of intra-cardiac four-dimensional flow cardiovascular magnetic resonance: A systematic review.
Synthesis in International journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03854071 (Development of Novel Physiological CMR Methods in Health and Disease), which is not on this map. Cited by 39 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development of Novel Physiological CMR Methods in Health and Disease
Who cites it
39 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Quality measurement for cardiovascular diseases and cancer in hospital value-based healthcare: a systematic review of the literature.BMC health services research · 2022Pooled it
- Four-dimensional flow cardiovascular magnetic resonance in tetralogy of Fallot: a systematic review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Pooled it
- A Systematic Review of 4D-Flow MRI Derived Mitral Regurgitation Quantification Methods.Frontiers in cardiovascular medicine · 2019Pooled it
- A Systematic Review of Right Ventricular Diastolic Assessment by 4D Flow CMR.BioMed research international · 2019Pooled it
- Clinical applications of intra-cardiac four-dimensional flow cardiovascular magnetic resonance: A systematic review.International journal of cardiology · 2017Pooled it
- Automated 4D flow MRI pipeline for the quantification of advanced hemodynamic parameters in the left atrium.Scientific reports · 2026Article
- Multimodality Imaging in Apical Hypertrophic Cardiomyopathy: Can Echocardiography Learn from Cardiac Magnetic Resonance?Diagnostics (Basel, Switzerland) · 2025Review
- Right heart flow hemodynamic assessment using 4D flow CMR: a systematic review.European heart journal. Imaging methods and practice · 2025Review
- Left ventricular diastolic inflow and myocardial flow reserve in patients with coronary artery disease: simultaneous analysis of 4D-Flow and myocardial perfusion using hybrid PETMR.The international journal of cardiovascular imaging · 2025Article
- Four-dimensional flow magnetic resonance assessment of alcohol septal ablation for hypertrophic obstructive cardiomyopathy and surgical valve replacement for aortic valve stenosis.Frontiers in cardiovascular medicine · 2025Article
- The effect of respiratory motion compensation in intracardiac 4D flow magnetic resonance imaging on left ventricular flow dynamics, multicomponent particle tracing, and valve tracking.European heart journal. Imaging methods and practice · 2025Article
- Feasibility of 4D-flow CMR for haemodynamic characterization in hypertrophic cardiomyopathy after septal myectomy with and without anterior mitral valve leaflet extension.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Age- and sex-specific reference values of biventricular flow components and kinetic energy by 4D flow cardiovascular magnetic resonance in healthy subjects.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Observational
- 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Review
- Quantifying Myocardial Blood Flow and Resistance Using 4D-Flow Cardiac Magnetic Resonance Imaging.Cardiology research and practice · 2023Article
- Visualizing diastolic failure: Non-invasive imaging-biomarkers in patients with heart failure with preserved ejection fraction.EBioMedicine · 2022Review
- Evaluation of Left Ventricular Function Using Four-Dimensional Flow Cardiovascular Magnetic Resonance: A Systematic Review.Journal of cardiovascular development and disease · 2022Review
- Interventions and measurement instruments used for falls efficacy in community-dwelling older adults: A systematic review.Journal of frailty, sarcopenia and falls · 2022Review
- Rationale and clinical applications of 4D flow cardiovascular magnetic resonance in assessment of valvular heart disease: a comprehensive review.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Review
- Four-dimensional flow cardiac magnetic resonance assessment of left ventricular diastolic function.Frontiers in cardiovascular medicine · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundFour-dimensional flow cardiovascular magnetic resonance (4D flow CMR) is an emerging non-invasive imaging technology used to visualise and quantify intra-cardiac blood flow. The aim of this systematic review is to assess the literature on the current clinical applications of intra-cardiac 4D flow CMR.
methodsA systematic review was conducted to evaluate the literature on the intra-cardiac clinical applications of 4D flow CMR. Structured searches were carried out on Medline, EMBASE and the Cochrane Library in October 2016. A modified Critical Skills Appraisal Programme (CASP) tool was used to objectively assess and score the included studies. Studies were categorised as 'highly clinically applicable' for scores of 67-100%, 'potentially clinically applicable' for 34-66% and 'less clinically applicable' for 0-33%.
resultsOf the 1608 articles screened, 44 studies met eligibility for systematic review. The included literature consisted of 22 (50%) mechanistic studies, 18 (40.9%) pilot studies and 4 (9.1%) diagnostic studies. Based on the modified CASP tool, 27 (62%) studies were 'highly clinically applicable', 9 (20%) were 'potentially clinically applicable' and 8 (18%) were 'less clinically applicable'.
conclusionsThere are many proposed methods for using 4D flow CMR to quantify intra-cardiac flow. The evidence base is mainly mechanistic, featuring single-centred designs. Larger, multi-centre studies are required to validate the proposed techniques and investigate the clinical advantages that 4D flow CMR offers over standard practices. PROSPERO=CRD42016051438.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.