Evidence map›Paper›PMID 28964532›Full record

ReviewOtolaryngologic clinics of North America2017

Contemporary Pharmacotherapy for Allergic Rhinitis and Chronic Rhinosinusitis.

Saied Ghadersohi, Bruce K Tan

Open access · greenAbstract readReview
In one paragraph

Review in Otolaryngologic clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Targetable pathogenic mechanisms in nasal polyposis.International forum of allergy & rhinology · 2021
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Saied GhadersohiDepartment of Otolaryngology-Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, 676 North Saint Clair Suite #1325, Chicago, IL 60611, USA.
Bruce K TanDepartment of Otolaryngology-Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, 676 North Saint Clair Suite #1325, Chicago, IL 60611, USA. Electronic address: btan@nm.org.
Northwestern University · US

Funding

Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisP01AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2013 to 2013
$1.7M
Role for B-cell mediated olfactory loss in Chronic Sinusitis with Nasal PolypsK23DC012067 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TAN, BRUCE K · 2012 to 2016
$1.1M
NIAID NIH HHS P01 AI106683NIDCD NIH HHS K23 DC012067
6 · The paper itself

Abstract

Chronic rhinosinusitis (CRS) and allergic rhinitis (AR) are chronic conditions causing nasal inflammation. CRS is increasingly recognized as a chronic inflammatory process rather than a chronic infection. Although the primary initiating factors in CRS remain unclear, AR is driven by IgE-mediated hypersensitivity to environmental allergens. Understanding the underlying inflammatory pathways and disease endotypes are driving innovation toward novel pharmacotherapies targeting critical mediators implicated in CRS and AR, including IL-4, IL-13, IL-5, IgE, and epithelial initiators IL-33 and TSLP. Extensive investigations are needed to determine the role, timing, predictive prognostic factors and long-term safety and efficacy of these agents.

Indexed as

AllergensAnti-Allergic AgentsBiological TherapyChronic DiseaseDesensitization, ImmunologicHumansImmunoglobulin EInterleukinsRandomized Controlled Trials as TopicRhinitis, AllergicSinusitisAllergensAnti-Allergic AgentsImmunoglobulin EInterleukinsBiologicsChronic rhinosinusitis (CRS)Immune specific targetingNovel pharmacotherapyType 2 inflammation

Identifiers

PMID28964532
PMCPMC5774623
OpenAlexW2758136498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.