Evidence map›Paper›PMID 28964260›Full record

Observational studyRespiratory research2017

Factors associated with hospitalization in bronchiectasis exacerbations: a one-year follow-up study.

Rosario Menéndez, Raúl Méndez, Eva Polverino, Edmundo Rosales-Mayor, Isabel Amara-Elori, Soledad Reyes, Tomás Posadas, Laia Fernández-Barat, Antoni Torres

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Respiratory research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

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  15. Isolated IgG2 deficiency is an independent risk factor for exacerbations in bronchiectasis.QJM : monthly journal of the Association of Physicians · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rosario MenéndezPneumology Department, Hospital Universitario y Politécnico La Fe / Instituto de Investigación Sanitaria (IIS) La Fe. University of Valencia, Valencia, Spain. rosmenend@gmail.com.ORCID 0000-0002-3592-3839
Raúl MéndezPneumology Department, Hospital Universitario y Politécnico La Fe / Instituto de Investigación Sanitaria (IIS) La Fe. University of Valencia, Valencia, Spain.
Eva PolverinoInstitut D' Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Edmundo Rosales-MayorInstitut D' Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
Isabel Amara-EloriPneumology Department, Hospital Universitario y Politécnico La Fe / Instituto de Investigación Sanitaria (IIS) La Fe. University of Valencia, Valencia, Spain.
Soledad ReyesPneumology Department, Hospital Universitario y Politécnico La Fe / Instituto de Investigación Sanitaria (IIS) La Fe. University of Valencia, Valencia, Spain.
Tomás PosadasPneumology Department, Hospital Universitario y Politécnico La Fe / Instituto de Investigación Sanitaria (IIS) La Fe. University of Valencia, Valencia, Spain.
Laia Fernández-BaratPneumology Department, Hospital Clínic / Institut D' Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS). University of Barcelona, Barcelona, Spain.
Antoni TorresPneumology Department, Hospital Clínic / Institut D' Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS). University of Barcelona, Barcelona, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESInstituto de Investigación Sanitaria La Fe · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchiectasis (BE) is a chronic structural lung disease with frequent exacerbations, some of which require hospital admission though no clear associated factors have been identified. We aimed to evaluate factors associated with hospitalization due to exacerbations during a 1-year follow-up period.

methodsA prospective observational study was performed in patients recruited from specialized BE clinics. We considered all exacerbations diagnosed and treated with antibiotics during a follow-up period of 1 year. The protocol recorded baseline variables, usual treatments, Bronchiectasis Severity Index (BSI) and FACED scores, comorbid conditions and prior hospitalizations.

resultsTwo hundred and 65 patients were recruited, of whom 162 required hospital admission during the follow-up period. Independent risk factors for hospital admission were age, previous hospitalization due to BE, use of proton pump inhibitors, heart failure, FACED and BSI, whereas pneumococcal vaccination was a protective factor. The area under the receiver operator characteristic curve (AUC) was 0.799 for BSI model was 0.799, and 0.813 for FACED model.

conclusionsPrevious hospitalization, use of proton pump inhibitors, heart failure along with BSI or FACED scores is associated factors for developing exacerbations that require hospitalization. Pneumococcal vaccination was protective. This information may be useful for the design of preventive strategies and more intensive follow-up plans.

Indexed as

Disease ProgressionAgedAged, 80 and overBronchiectasisFemaleFollow-Up StudiesHeart FailureHospitalizationHumansMaleMiddle AgedProspective StudiesProton Pump InhibitorsRisk FactorsSeverity of Illness IndexProton Pump Inhibitors

Identifiers

PMID28964260
PMCPMC5622554
OpenAlexW2760102695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.