Evidence map›Paper›PMID 28963853›Full record

Trial reportAddiction (Abingdon, England)2018

The effect of a behavioral activation treatment for substance use on post-treatment abstinence: a randomized controlled trial.

Stacey B Daughters, Jessica F Magidson, Deepika Anand, C J Seitz-Brown, Yun Chen, Sydney Baker

4 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 86 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 4 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03705143 nacompletednot on this map

The Behavioral Activation for Chinese Substance Users (C-BA) Research Protocol

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2018 to 2018Enrolled90ConditionsSubstance-Related Disorders, Mood Disorders, Behavioral Activation Treatment, Mental DisordersArmsTreatment as usual, Chinese translated LETS ACT
NCT05086172 nacompletednot on this mapstarted 2022, after this paper: background citation

Ultrabrief Behavioral Activation for Reducing Alcohol Use

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2022 to 2023Enrolled40ConditionsAlcohol Use Disorder, Mild, Alcohol Use Disorder, ModerateArmsUltrabrief Behavioral Activation
NCT05299515 nacompletednot on this mapstarted 2022, after this paper: background citation

Peer-Delivered Behavioral Activation Intervention to Improve Adherence to MT Among Low-Income, Minority Individuals With OUD

TypeinterventionalSponsorUniversity of Maryland, College ParkRan2022 to 2025Enrolled200ConditionsSubstance-Related Disorders, Opioid Medication Assisted Treatment, Opioid Use Disorder, Opioid UseArmsPeer-Delivered Behavioral Activation ("Peer Activate")
NCT05973838 narecruitingnot on this mapstarted 2023, after this paper: background citation

Peer-Delivered, Behavioral Activation Intervention to Improve Polysubstance Use and Retention in Mobile Telemedicine OUD Treatment in an Underserved, Rural Area

TypeinterventionalSponsorUniversity of Maryland, College ParkRan2023 to 2027Enrolled160ConditionsPolysubstance Addiction, Opioid Medication Assisted Treatment, Treatment Adherence, Retention in CareArmsPeer-Delivered Behavioral Activation ("Peer Activate")
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 4 syntheses or guidelines pooled it, 190 citations in OpenAlex.

  1. Pooled it
  2. Interventions for female drug-using offenders.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Pooled it
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  7. Behavioral Activation mHealth Application for Smoking Cessation: A Randomized Controlled Pilot Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024
    Trial
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  13. A pilot trial of a brief intervention for cannabis use supplemented with a substance-free activity session or relaxation training.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Trial
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  16. A randomized pilot trial of a mobile delivered brief motivational interviewing and behavioral economic alcohol intervention for emerging adults.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Trial
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Stacey B DaughtersDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0001-5075-030X
Jessica F MagidsonDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Deepika AnandDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
C J Seitz-BrownDepartment of Psychology, University of Maryland, College Park, MD, USA.
Yun ChenDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sydney BakerDepartment of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USHarvard University · USUniversity of Maryland, College Park · US

Funding

Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Technology Enhanced Behavioral Activation Treatment for Substance UseR01DA026424 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAUGHTERS, STACEY B · 2010 to 2019
$4.4M
Minority Populations Prevention Researcher TrainingR25HD045810 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NEILANDS, TORSTEN BRIAN · 2003 to 2018
$4.3M
Behavioral Depression Treatment for African American HIV-infected Substance UsersR01DA022974 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI LEJUEZ, CARL W · 2008 to 2011
$1.4M
Hybrid Effectiveness-Implementation Trial for ART Adherence and Substance Use in HIV Care in South AfricaK23DA041901 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F · 2016 to 2020
$1.0M
NICHD NIH HHS R25 HD045810NIDA NIH HHS K23 DA041901NIDA NIH HHS R01 DA022974NIDA NIH HHS R01 DA026424NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

aimsTo compare outcomes for a behavioral activation group treatment for substance use [life enhancement treatment for substance use (LETS ACT)] versus a time and group size-matched control condition delivered in a residential treatment setting.

designSingle-site two-arm parallel-group randomized clinical trial with follow-up assessment at 3, 6 and 12 months post-treatment.

settingResidential substance use treatment facility in the United States.

participantsParticipants were 263 adults [mean age 42.7 (11.8); 29.5% female; 95.4% African American; 73.2% court mandated] whose insurance dictated 30-day (65.9%) or 90-day (34.1%) treatment duration. INTERVENTION AND COMPARATOR: LETS ACT (n = 142) is a treatment developed originally for depression and modified for substance use. It teaches participants to increase positively reinforcing value-driven activities in order to counter depression and relapse. The control group [supportive counseling (SC); n = 121] received time and group size-matched supportive counseling. Treatment was delivered in five or eight 1-hour sessions depending on patient length of stay. MEASUREMENTS: Percentage abstinent at follow-up, percentage of substance use days among those reporting use, depressive symptoms [Beck Depression Inventory (BDI)] and adverse consequences of drug use [Short Inventory of Problems-Alcohol and Drug (SIP-AD)].

findingsLETS ACT had significantly higher abstinence rates at 3 months [odds ratio (OR) = 2.2, 95% confidence interval (CI) = 1.3-3.7], 6 months (OR = 2.6, 95% CI= 1.3-5.0) and 12 months (OR = 2.9, 95% CI = 1.3-6.1) post-treatment compared with SC. LETS ACT participants reported significantly fewer adverse consequences from substance use at 12 months post-treatment [B = 4.50, standard error (SE) = 2.17, 95% CI = 0.22-8.78]. Treatment condition had no effect on percentage substance use days among those who resumed use or on change in depressive symptoms; the latter decreased over time only in those who remained abstinent after residential treatment irrespective of condition (B = 0.43, SE = 0.11, 95% confidence interval = 0.22-0.65).

conclusionsA behavioral activation group treatment for substance use (LETS ACT) appears to increase the likelihood of abstinence and reduce adverse consequences from substance use up to 12 months post-treatment.

Indexed as

AdultBehavior TherapyDistrict of ColumbiaFemaleFollow-Up StudiesHumansMaleResidential TreatmentSubstance-Related DisordersTreatment OutcomeAbstinencebehavioral activationdepressionpost-treatmentrelapseresidentialsubstance usetreatment

Identifiers

PMID28963853
PMCPMC5807178
OpenAlexW2760626533

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.