ArticleEuropean radiology2018
Prognostic value of coronary atherosclerosis progression evaluated by coronary CT angiography in patients with stable angina.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Non-invasive imaging of atherosclerosis progression and cardiovascular outcome: a systematic review and meta-analysis.The international journal of cardiovascular imaging · 2026Review
- Comprehensive risk prediction of acute coronary syndrome by integrating coronary plaque morphology and hemodynamic characteristics.Quantitative imaging in medicine and surgery · 2026Article
- Incremental prognostic value of CCTA-based myocardial radiomics over clinical factors, anatomic and hemodynamic CTA findings in patients with stable angina.The international journal of cardiovascular imaging · 2026Review
- The role of nuclear imaging in detection of coronary artery disease: a comprehensive review.American journal of translational research · 2026Review
- Role of Cardiovascular Imaging in Risk Assessment: Recent Advances, Gaps in Evidence, and Future Directions.Journal of clinical medicine · 2023Review
- Does Coronary Plaque Morphology Matter Beyond Plaque Burden?Current atherosclerosis reports · 2023Review
- Association between Coronary Artery Plaque Progression and Liver Fibrosis Biomarkers in Population with Low Calcium Scores.Nutrients · 2022Article
- Effect of long-term intensive cholesterol control on the plaque progression in elderly based on CTA cohort study.European radiology · 2022Article
- Current Progress of Studies of Coronary CT for Risk Prediction of Major Adverse Cardiovascular Event (MACE).Journal of cardiovascular imaging · 2021Review
- Serial coronary CT angiography-derived fractional flow reserve and plaque progression can predict long-term outcomes of coronary artery disease.European radiology · 2021Article
- Comparison of Predictive Ability of Computed Tomography and Magnetic Resonance Imaging in Patients with Carotid Atherosclerosis Complicated with Stroke.Iranian journal of public health · 2019Article
- The effect of heart rate on coronary plaque measurements in 320-row coronary CT angiography.The international journal of cardiovascular imaging · 2018Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo investigate the progression of coronary atherosclerosis burden by coronary CT angiography (CCTA) and to demonstrate its association with the incidence of major adverse cardiac events (MACE).
methodsWe retrospectively studied patients with stable angina who had undergone repeat CCTA due to recurrent or worsening symptoms. Lipid-rich, fibrous, calcified and total plaque burden as well as coronary diameter stenosis were quantitatively analysed. The incidence of MACE during follow-up was determined.
resultsThe final cohort consisted of 268 patients (mean age 52.9 ± 9.8 years, 71 % male) with a mean follow-up period of 4.6 ± 0.9 years. Patients with lipid-rich, fibrous, calcified and total plaque burden (%) progression, as well as coronary diameter stenosis (%) progression had a significantly higher incidence of MACE than those without (all p < 0.05). The progression of lipid-rich plaque (HR = 1.601, p = 0.021), total plaque burden (HR = 2.979, p = 0.043) and coronary diameter stenosis (HR = 4.327, p <0.001) were independent predictors of MACE (all p < 0.05).
conclusionsPatients presenting with recurrent or worsening symptoms associated with coronary artery disease who have coronary atherosclerosis progression on CCTA are at an increased risk of future MACE. KEY POINTS: • Repeat CCTA can provide information regarding the progression of coronary atherosclerosis. • Coronary atherosclerosis progression at CCTA is independently associated with MACE. • CCTA findings could serve as incremental predictors of MACE.
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