ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2017
Evaluation of startle response and prepulse inhibition based on changes in the range of vertical pressure force of the feet on the ground: a preliminary study.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The aim of the study was to evaluate the possibility of estimating a startle response and sensorimotor gating based on changes in the range of vertical pressure force of the feet on the ground during a dynamometric examination. The study encompassed 13 healthy and physically fit men (age: 23.3 ± 2.0 years; height: 178.0 ± 6.1 cm; and weight: 76.1 ± 9.0 kg). The inhibitory mechanisms of startle reflex were used as the measure of sensorimotor gating. It was triggered by a strong acoustic stimulus (106 dB SPL, 40 ms), which was preceded by a similar, weaker signal (80 dB SPL, 20 ms). Startle reflex was evaluated using a piezoelectric force platform. The results of the conducted study show that the range of vertical pressure force of the feet caused by the reaction to a strong acoustic stimulus is significantly smaller when this stimulus is preceded by a signal of lower intensity (prepulse). Such assessment is only possible with the participants' eyes open. The generalized startle response of a person may be estimated using a force platform, based on changes in the range of vertical pressure force of the feet on the ground, which are caused by unexpected acoustic stimuli. There is a strong indication that using a force platform to evaluate sensorimotor gating could be used as an alternative to electromyographic examinations.
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