Evidence map›Paper›PMID 28963525›Full record

ArticleScientific reports2017

Phyto-mediated metallic nano-architectures via Melissa officinalis L.: synthesis, characterization and biological properties.

Irina Fierascu, Milen I Georgiev, Alina Ortan, Radu Claudiu Fierascu, Sorin Marius Avramescu, Daniela Ionescu, Anca Sutan, Alexandru Brinzan, Lia Mara Ditu

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Green Synthesis of Silver Nanoparticles fromMolecules (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
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  10. International journal of molecular sciences · 2022
    Review
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  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Molecules (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Irina FierascuUniversity of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 011464, Bucharest, Romania.
Milen I GeorgievUniversity of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 011464, Bucharest, Romania.
Alina OrtanUniversity of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 011464, Bucharest, Romania. alina_ortan@hotmail.com.
Radu Claudiu FierascuUniversity of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 011464, Bucharest, Romania. radu_claudiu_fierascu@yahoo.com.
Sorin Marius AvramescuUniversity of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 011464, Bucharest, Romania.
Daniela IonescuUniversity of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 011464, Bucharest, Romania.
Anca SutanUniversity of Pitesti, Faculty of Science, 1 Targu din Vale Str, 110040, Pitesti, Romania.
Alexandru BrinzanRomanian Academy, Institute of Biology - Bucharest, 296 Spl. Independentei, 060031, Bucharest, Romania.
Lia Mara DituUniversity of Bucharest, Microbiology Department, 1-3 Aleea Portocalelor, 060101, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of methods for obtaining new materials with antimicrobial properties, based on green chemistry principles has been a target of research over the past few years. The present paper describes the phyto-mediated synthesis of metallic nano-architectures (gold and silver) via an ethanolic extract of Melissa officinalis L. (obtained by accelerated solvent extraction). Different analytic methods were applied for the evaluation of the extract composition, as well as for the characterization of the phyto-synthesized materials. The cytogenotoxicity of the synthesized materials was evaluated by Allium cepa assay, while the antimicrobial activity was examined by applying both qualitative and quantitative methods. The results demonstrate the synthesis of silver nanoparticles (average diameter 13 nm) and gold nanoparticles (diameter of ca. 10 nm); the bi-metallic nanoparticles proved to have a core-shell flower-like structure, composed of smaller particles (ca. 8 nm). The Ag nanoparticles were found not active on nuclear DNA damage. The Au nanoparticles appeared nucleoprotective, but were aggressive in generating clastogenic aberrations in A. cepa root meristematic cells. Results of the antimicrobial assays show that silver nanoparticles were active against most of the tested strains, as the lowest MIC value being obtained against B. cereus (approx. 0.0015 mM).

Indexed as

Anti-Infective AgentsCandidaCell SurvivalCinnamatesDNA DamageFlavonoidsGoldGram-Negative BacteriaGram-Positive BacteriaGreen Chemistry TechnologyMelissaMetal NanoparticlesMethanolMicrobial Sensitivity TestsOnionsParticle SizeAnti-Infective AgentsCinnamatesFlavonoidsGoldMethanolPlant ExtractsSilverSolvents

Identifiers

PMID28963525
PMCPMC5622205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.