Evidence map›Paper›PMID 28963367›Full record

ArticleJournal of neurointerventional surgery2018

TREVO stent-retriever mechanical thrombectomy for acute ischemic stroke secondary to large vessel occlusion registry.

Osama O Zaidat, Alicia C Castonguay, Raul G Nogueira, Diogo C Haussen, Joey D English, Sudhakar R Satti, Jennifer Chen, Hamed Farid, Candace Borders, Erol Veznedaroglu and 20 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05403593 (Registry of Emergent Large VeSsel OCclUsion DuE to IntraCranial AtherosclerosiS), which is not on this map. Cited by 60 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05403593 completednot on this mapstarted 2021, after this paper: background citation

Registry of Emergent Large VeSsel OCclUsion DuE to IntraCranial AtherosclerosiS

Typeobservational_patient_registrySponsorMedical University of South CarolinaRan2021 to 2024Enrolled600ConditionsIntracranial Stenosis, Large Vessel Occlusion, Mechanical ThrombectomyArmsNo Intervention
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. SOFIA catheter for direct aspiration of large vessel occlusion stroke: A single-center cohort and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Pooled it
  3. Guideline
  4. Pooled it
  5. Trial
  6. One-year single-center experience with the Aperio thrombectomy device in large vessel occlusion in the anterior circulation: safety, efficacy, and clinical outcome.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019
    Trial
  7. Article
  8. Mechanical thrombectomy with a new intermediate balloon catheter combining the BGC and DAC features: Initial clinical experience with the iNedit device.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  9. Article
  10. Effect of Anesthesia on Functional Outcomes in Acute Ischemic Stroke Patients Undergoing Thrombectomy with the RECO Device.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  11. Impacts of Oxylipins on ischemic stroke: from pathophysiology to clinical phenotypes.Metabolomics : Official journal of the Metabolomic Society · 2025
    Review
  12. Article
  13. Effectiveness and safety of the Trevo® Retriever for mechanical thrombectomy in Chinese patients with acute ischemic stroke: Trevo Retriever China Registry.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Osama O ZaidatDepartments of Endovascular Neurosurgery and Stroke, St Vincent Mercy Medical Center, Toledo, Ohio, USA.
Alicia C CastonguayDepartment of Biostatistics, University of Texas, Houston, Texas, USA.
Raul G NogueiraDepartment of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
Diogo C HaussenDepartment of Neurology, Emory University School of Medicine, Atlanta, Georgia, USA.
Joey D EnglishCalifornia Pacific Medical Center, Atlanta, Florida, USA.
Sudhakar R SattiDepartment of Neurointerventional Surgery, Christiana Care Health System, Newark, Delaware, USA.
Jennifer ChenSidney Kimmel Medical College, Philadelphia, Pennsylvania, USA.
Hamed FaridDepartment of Neurointerventional Radiology, St Jude Medical Center, Fullerton, USA.
Candace BordersUniversity of California, Irvine School of Medicine, Irvine, California, USA.
Erol VeznedarogluDepartment of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, Pennsylvania, USA.
Mandy J BinningDepartment of Neurosurgery, Drexel Neurosciences Institute, Philadelphia, Pennsylvania, USA.
Ajit PuriDepartment of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Nirav A VoraDepartment of Radiology, Riverside Radiology and Interventional Associates, Columbus, Ohio, USA.
Ron F BudzikDepartment of Radiology, Riverside Radiology and Interventional Associates, Columbus, Ohio, USA.
Guilherme DabusDepartment of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, Miami, Florida, USA.
Italo LinfanteDepartment of Neurointerventional Surgery, Baptist Cardiac and Vascular Institute, Miami, Florida, USA.
Vallabh JanardhanTexas Stroke Institute, Plano, Texas, USA.
Amer AlshekhleeDepartment of Vascular and Interventional Neurology, DePaul Stroke Center-SSM Neuroscience Institutes, St Louis University, St Louis, Missouri, USA.
Michael G AbrahamDepartments of Neurology and Interventional Radiology, University of Kansas Medical Center, Kansas, USA.
Randall EdgellDepartment of Neurology, St Louis University, St Louis, Missouri, USA.
Muhammad Asif TaqiDepartment of Neurology and Neurosurgery, Los Robles Hospital and Medical Center, Thousand Oaks, California, USA.
Ramy El KhouryDepartment of Neurology, Tulane University, New Orleans, Louisiana, USA.
Maxim MokinDepartment of Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida, USA.
Aniel Q MajjhooDepartment of Neurology, Wayne State School of Medicine, Detroit, Michigan, USA.
Mouhammed R KabbaniDepartment of Neurosurgery, Gundersen Health System, La Crosse, Wisconsin, USA.
Michael T FroehlerDepartments of Neurology, Neurosurgery, and Radiology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ira FinchJohn Muir Health, Walnut Creek, California, USA.
Sameer A AnsariDepartments of Radiology, Neurology, and Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Roberta NovakovicDepartments of Radiology, Neurology, and Neurotherapeutics, UT Southwestern Medical Center, Dallas, Texas, USA.
Thanh N NguyenDepartment of Neurology, Neurosurgery, and Radiology, Boston Medical Center, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent randomized clinical trials (RCTs) demonstrated the efficacy of mechanical thrombectomy using stent-retrievers in patients with acute ischemic stroke (AIS) with large vessel occlusions; however, it remains unclear if these results translate to a real-world setting. The TREVO Stent-Retriever Acute Stroke (TRACK) multicenter Registry aimed to evaluate the use of the Trevo device in everyday clinical practice.

methodsTwenty-three centers enrolled consecutive AIS patients treated from March 2013 through August 2015 with the Trevo device. The primary outcome was defined as achieving a Thrombolysis in Cerebral Infarction (TICI) score of ≥2b. Secondary outcomes included 90-day modified Rankin Scale (mRS), mortality, and symptomatic intracranial hemorrhage (sICH).

resultsA total of 634patients were included. Mean age was 66.1±14.8 years and mean baseline NIH Stroke Scale (NIHSS) score was 17.4±6.7; 86.7% had an anterior circulation occlusion. Mean time from symptom onset to puncture and time to revascularization were 363.1±264.5 min and 78.8±49.6 min, respectively. 80.3% achieved TICI ≥2b. 90-day mRS ≤2 was achieved in 47.9%, compared with 51.4% when restricting the analysis to the anterior circulation and within 6 hours (similar to recent AHA/ASA guidelines), and 54.3% for those who achieved complete revascularization. The 90-day mortality rate was 19.8%. Independent predictors of clinical outcome included age, baseline NIHSS, use of balloon guide catheter, revascularization, and sICH.

conclusionThe TRACK Registry results demonstrate the generalizability of the recent thrombectomy RCTs in real-world clinical practice. No differences in clinical and angiographic outcomes were shown between patients treated within the AHA/ASA guidelines and those treated outside the recommendations.

Indexed as

RegistriesStentsAgedAged, 80 and overBrain IschemiaCerebrovascular DisordersFemaleHumansMaleMiddle AgedProspective StudiesRetrospective StudiesStrokeThrombectomyTreatment Outcomemechanicalrevascularizationstent-retrieverstrokethrombectomytrevo

Identifiers

PMID28963367
PMCPMC5969387

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.