Evidence map›Paper›PMID 28963303›Full record

Trial reportBMJ open2017

Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol.

Ryan Ottridge, Susan P Mollan, Hannah Botfield, Emma Frew, Natalie J Ives, Tim Matthews, James Mitchell, Caroline Rick, Rishi Singhal, Rebecca Woolley and 1 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02124486 (A Randomised Controlled Trial of Bariatric Surgery Versus a Community Weight Loss Programme for the Sustained Treatment of Idiopathic Intracranial Hypertension), which is not on this map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02124486 naunknown statusnot on this map

A Randomised Controlled Trial of Bariatric Surgery Versus a Community Weight Loss Programme for the Sustained Treatment of Idiopathic Intracranial Hypertension: the IIH:WT Trial

TypeinterventionalSponsorUniversity of BirminghamRan2014 to 2022Enrolled90ConditionsIdiopathic Intracranial HypertensionArmsBariatric surgery, Dietetic intervention
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ryan OttridgeBirmingham Clinical Trials Unit, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Susan P MollanBirmingham Neuro-Ophthalmology Unit, University Hospitals Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
Hannah BotfieldInstitute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Emma FrewInstitute of Applied Health Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Natalie J IvesBirmingham Clinical Trials Unit, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Tim MatthewsBirmingham Neuro-Ophthalmology Unit, University Hospitals Birmingham, Queen Elizabeth Hospital, Birmingham, UK.
James MitchellInstitute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Caroline RickBirmingham Clinical Trials Unit, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Rishi SinghalUpper GI and Minimally Invasive Unit, Heartlands Hospital, Birmingham, UK.
Rebecca WoolleyBirmingham Clinical Trials Unit, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
Alexandra J SinclairInstitute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
University of Birmingham · GBCancer Research UK Clinical Trials Unit · GBQueen Elizabeth Hospital Birmingham · GBHeartlands Hospital · GB

Funding

Department of Health NIHR-CS-011-028Wellcome Trust
6 · The paper itself

Abstract

introductionEffective treatments are lacking for idiopathic intracranial hypertension (IIH), a condition characterised by raised intracranial pressure (ICP) and papilloedema, and found primarily in obese women. Weight loss and lowering body mass index (BMI) have been shown to lower ICP and improve symptoms in IIH; however, weight loss is typically not maintained, meaning IIH symptoms return. The Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) will assess whether bariatric surgery is an effective long-term treatment for patients with IIH with a BMI over 35 kg/m METHODS AND ANALYSIS: IIH:WT is a multicentre, open-label, randomised controlled clinical trial of 64 participants with active IIH and a BMI over 35 kg/m TRIAL REGISTRATION NUMBER: IIH:WT is registered as ISRCTN40152829 and on ClinicalTrials.gov as NCT02124486 and is in the pre-results stage.

Indexed as

Bariatric SurgeryBody Mass IndexWeight Reduction ProgramsBody WeightCost-Benefit AnalysisFemaleHumansLinear ModelsObesityPseudotumor CerebriQuality of LifeResearch DesignTreatment OutcomeUnited KingdomWeight Lossbariatric surgerydietIdiopathic intracranial hypertensionweight loss

Identifiers

PMID28963303
PMCPMC5623580
OpenAlexW2758597538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.