Evidence map›Paper›PMID 28962450›Full record

ArticleToxicology reports2015

Acute and subchronic toxicity of the antitumor agent rhodium (II) citrate in Balb/c mice after intraperitoneal administration.

Marcella L B Carneiro, Cláudio A P Lopes, Ana L Miranda-Vilela, Graziella A Joanitti, Izabel C R da Silva, Márcia R Mortari, Aparecido R de Souza, Sônia N Báo

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PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marcella L B CarneiroFaculty of Planaltina, University of Brasília (UnB), 73.345-010, Brazil.
Cláudio A P LopesInstitute of Biological Sciences, Department of Cell Biology, University of Brasília (UnB), 70.910-900, Brazil.
Ana L Miranda-VilelaInstitute of Biological Sciences, Department of Genetics and Morphology, University of Brasília (UnB), 70.910-900, Brazil.
Graziella A JoanittiFaculty of Ceilândia, University of Brasília, Brasília, 72220-900, Brazil.
Izabel C R da SilvaFaculty of Ceilândia, University of Brasília, Brasília, 72220-900, Brazil.
Márcia R MortariInstitute of Biological Sciences, Department of Physiological Sciences, University of Brasília (UnB), 70.910-900, Brazil.
Aparecido R de SouzaInstitute of Chemistry, Federal University of Goiás, Campus Samambaia, Goiânia, Goiás, 74.001-970, Brazil.
Sônia N BáoInstitute of Biological Sciences, Department of Cell Biology, University of Brasília (UnB), 70.910-900, Brazil.
Universidade de Brasília · BRUniversidade Federal de Goiás · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate potential acute and subchronic toxicity of rhodium (II) citrate in female Balb/c mice after intraperitoneal injections. In the acute test, independent groups received five doses; the highest dose (107.5 mg/kg) was equivalent to 33 times that used in our previous reports. The other doses were chosen as proportions of the highest, being 80.7 (75%), 53.8 (50%), 26.9 (25%) or 13.8 mg/kg (12.5%). Animals were monitored over 38 days and no severe signs of toxicity were observed, according to mortality, monitoring of adverse symptoms, hematological, biochemical and genotoxic parameters. We conclude that the median lethal dose (LD

Indexed as

Acute and subchronic toxicityBiochemical and hematological analysisGenotoxicityHistopathologylethal doseToxicological analysis

Identifiers

PMID28962450
PMCPMC5598461
OpenAlexW1126512853

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.