Evidence map›Paper›PMID 28962402›Full record

ArticleToxicology reports2015

Supplemental dietary phytosterin protects against 4-nitrophenol-induced oxidative stress and apoptosis in rat testes.

Yonghui Zhang, Meiyan Song, Xiaoli Rui, Shaoxia Pu, Yansen Li, ChunMei Li

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yonghui ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.
Meiyan SongCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.
Xiaoli RuiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.
Shaoxia PuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.
Yansen LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.
ChunMei LiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, PR China.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

4-Nitrophenol (PNP), is generally regarded as an environmental endocrine disruptor (EED). Phytosterin (PS), a new feed additive, possesses highly efficient antioxidant activities. The transcription factor, nuclear factor-erythroid 2-related factor 2 (Nrf2), is an important regulator of cellular oxidative stress. Using rats, this study examined PNP-induced testicular oxidative damage and PS-mediated protection against that damage. The generation of MDA and H

Indexed as

4-Nitrophenol4-Nitrophenol (PubChem CID: 980)Antioxidant geneApoptosisARE, antioxidant response elementCampesterol (PubChem CID: 457801)CAT, catalaseDEP, diesel exhaust particlesEED, environmental endocrine disruptorGCLC, γ-glutamylcysteine synthetaseGSH, glutathioneGSH-Px, glutathione peroxidaseHO-1, heme oxygenase 1Keap1, kelch-like ECH-associated protein 1NF-κB, nuclear factor-κBNQO1, NAD(P)H: quinone oxidoreductase 1Nrf2Nrf2, nuclear factor erythroid 2-related factor 2PhytosterinPNP, 4-nitrophenolPS, phytosterinsROS, reactive oxygen speciesSOD, superoxide dismutaseStigmasterol (PubChem CID: 5280794)Testisβ-Sitosterol (PubChem CID: 222284)

Identifiers

PMID28962402
PMCPMC5598167
OpenAlexW313962503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.