Evidence map›Paper›PMID 28962369›Full record

ArticleToxicology reports2015

Systemic inflammatory responses following welding inhalation challenge test.

Paula Kauppi, Merja Järvelä, Timo Tuomi, Ritva Luukkonen, Tuula Lindholm, Riina Nieminen, Eeva Moilanen, Timo Hannu

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Fractional exhaled NO in a metalworking occupational cohort.International archives of occupational and environmental health · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Paula KauppiUniversity of Helsinki and Helsinki University (Central) Hospital, Respiratory Diseases and Allergology, Helsinki, Finland.
Merja JärveläAerosols, Dusts and Metals, Finnish Institute of Occupational Health, Helsinki, Finland.
Timo TuomiAerosols, Dusts and Metals, Finnish Institute of Occupational Health, Helsinki, Finland.
Ritva LuukkonenStatistical Services, Finnish Institute of Occupational Health, Helsinki, Finland.
Tuula LindholmPhysical Work Capacity, Finnish Institute of Occupational Health, Helsinki, Finland.
Riina NieminenThe Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
Eeva MoilanenThe Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland.
Timo HannuOccupational Medicine, Finnish Institute of Occupational Health, Helsinki, Finland.
Finnish Institute of Occupational Health · FITampere University · FITampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to investigate inflammatory and respiratory responses to welding fume exposure in patients with suspected occupational asthma.

methodsSixteen patients referred to the Finnish Institute of Occupational Health underwent mild steel (MS) and stainless steel (SS) welding challenge tests, due to suspicion of OA. Platelet count, leucocytes and their differential count, hemoglobin, sensitive CRP, lipids, glucose and fibrinogen were analyzed in addition to interleukin (IL)-1β, IL-6, IL-8, TNF-α, endothelin-1, and E-selectin in plasma samples. Peak expiratory flow (PEF), forced expiratory volume in 1 min (FEV

resultsThe number of leukocytes, neutrophils, and platelets increased significantly, and the hemoglobin level and number of erythrocytes decreased significantly after both the MS and SS exposure tests. Five of the patients were diagnosed with OA, and their maximum fall in FEV

conclusionsExposure to MS and SS welding fume resulted in a mild systemic inflammatory response. The particle concentration from the breathing zones correlated with the measurements inside the welding face shields.

Indexed as

Chromium (PubMed CID: 23976)CytokinesExposureIron (PubMed CID: 23925)Manganese (PubMed CID: 23930)Mild steelNickel (PubMed CID: 935)Occupational asthmaStainless steelWelding

Identifiers

PMID28962369
PMCPMC5598409
OpenAlexW2077337621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.