ArticleToxicology reports2015
Protective effects of hesperidin on oxidative stress, dyslipidaemia and histological changes in iron-induced hepatic and renal toxicity in rats.
Article in Toxicology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 106 citations in OpenAlex.
- Quercetin and hesperidin attenuate cyclophosphamide-induced renal injury in rats.Journal of molecular histology · 2026Article
- Hesperidin: A Multifunctional Flavonoid with Therapeutic Potential in the Management of Pathogenesis.International journal of molecular sciences · 2026Review
- Effects of hesperidin and ascorbic acid combination on boar sperm quality during cryopreservation.Frontiers in veterinary science · 2025Article
- The Browning Properties, Antioxidant Activity, and α-Glucosidase Inhibitory Improvement of Aged Oranges (Foods (Basel, Switzerland) · 2024Article
- Natural compounds proposed for the management of non-alcoholic fatty liver disease.Natural products and bioprospecting · 2024Review
- Iron overload induced submandibular glands toxicity in gamma irradiated rats with possible mitigation by hesperidin and rutin.BMC pharmacology & toxicology · 2024Article
- The renoprotective effects of hesperidin on kidney injury induced by exposure to severe chronic dust storm particulate matter through inhibiting the Smads/TGF-β1 signaling in rat.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Article
- Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.Cell cycle (Georgetown, Tex.) · 2023Article
- Effect of Vitamin E on Apoptosis of the Endothelial Cells of the Carotid Arteries in Hypercholesterolemic Male Rabbits.ARYA atherosclerosis · 2023Article
- Antioxidant and Lipid-Lowering Effects of Buriti Oil (Molecules (Basel, Switzerland) · 2023Article
- Article
- Protective effects of hesperidin in cyclophosphamide-induced parotid toxicity in rats.Scientific reports · 2023Article
- Hormonal and inflammatory modulatory effects of hesperidin in hyperthyroidism-modeled rats.Frontiers in immunology · 2023Article
- Biochemical and pharmacological prospects ofHeliyon · 2022Article
- Hesperidin ameliorates cisplatin induced hepatotoxicity and attenuates oxidative damage, cell apoptosis, and inflammation in rats.Saudi journal of biological sciences · 2022Article
- Protective and Therapeutic Efficacy of Hesperidin versus Cisplatin against Ehrlich Ascites Carcinoma-Induced Renal Damage in Mice.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Hesperidin Preserves Cognitive Functions and Hippocampus Histological Architecture in Albino Wistar Rats Subjected to Stress Through Enhancement of Brain-Derived Neurotrophic Factor.Neurotoxicity research · 2022Article
- Hesperidin protects rats' liver and kidney from oxidative damage and physiological disruption induced by nickel oxide nanoparticles.Frontiers in physiology · 2022Article
- Evaluation of the effects of hesperidin on fresh and frozen-thawed semen quality using two different cryopreservation methods in Simmental bull.Animal reproduction · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study was to evaluate the protective role of hesperidin (HDN) against iron-induced hepatic and renal toxicity in rats. Administration of iron (30 mg/kg body weight) intraperitoneally for 10 days, the levels of serum hepatic markers, renal functional markers, lipid profile, lipid peroxidation markers and iron concentration in blood were significantly (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.