Evidence map›Paper›PMID 28962246›Full record

ArticleToxicology reports2014

Ameliorative effect of Koflet formulations against pyridine-induced pharyngitis in rats.

G L Viswanatha, Mohamed Rafiq, A H M Thippeswamy, H C Yuvaraj, K J Kavya, Mirza Rizwan Baig, D A Suryakanth, Mohammed Azeemuddin, P S Patki, H B Pushpalatha and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Antipharyngitis Effects ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  3. Lysozyme in the treatment of non-infectious sore throat.Bosnian journal of basic medical sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

G L ViswanathaDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
Mohamed RafiqDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
A H M ThippeswamyDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
H C YuvarajDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
K J KavyaDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
Mirza Rizwan BaigDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
D A SuryakanthDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
Mohammed AzeemuddinDepartment of Pharmacology, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
P S PatkiHead-Medical Services & Clinical Trials, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
H B PushpalathaFormulation & Development, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
Prafulla S ChaudhariFormulation & Development, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.
Ramakrishnan ShyamChief Scientific Officer, R&D Center, The Himalaya Drug Company, Bangalore 562 162, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In present study two formulations of Koflet (syrup and lozenges) were evaluated against pyridine-induced pharyngitis in rats. Topical application of 10% pyridine showed extravasation of Evans blue stain as a characteristic feature of on-going inflammation. In addition, the levels of TNF-α (

Indexed as

KofletNon-infectious pharyngitisNovel animal modelPharyngitisPyridine

Identifiers

PMID28962246
PMCPMC5598515
OpenAlexW1995578997

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.