Evidence map›Paper›PMID 28962227›Full record

ArticleToxicology reports2014

A novel aromatic mutagen, 5-amino-6-hydroxy-8

Takahiro Kochi, Masahito Shimizu, Yukari Totsuka, Yohei Shirakami, Takayuki Nakanishi, Tetsushi Watanabe, Takuji Tanaka, Hitoshi Nakagama, Keiji Wakabayashi, Hisataka Moriwaki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Mutagenicity of carcinogenic heterocyclic amines in Salmonella typhimurium YG strains and transgenic rodents including gpt delta.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2021
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Takahiro KochiDepartment of Internal Medicine/Gastroenterology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Masahito ShimizuDepartment of Internal Medicine/Gastroenterology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Yukari TotsukaDivision of Cancer Development System, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.
Yohei ShirakamiDepartment of Internal Medicine/Gastroenterology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Takayuki NakanishiDepartment of Internal Medicine/Gastroenterology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Tetsushi WatanabeDepartment of Public Health, Kyoto Pharmaceutical University, 1 Shichono-cho, Misasagi, Yamashina-ku, Kyoto 607-8412, Japan.
Takuji TanakaDepartment of Tumor Pathology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Hitoshi NakagamaDivision of Cancer Development System, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.
Keiji WakabayashiDivision of Nutritional and Environmental Sciences, Institute for Environmental Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan.
Hisataka MoriwakiDepartment of Internal Medicine/Gastroenterology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
Gifu University · JPInstitute for Environmental Sciences · JPKyoto Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The benzoazepinoqunolinone derivative, 5-amino-6-hydroxy-8

Indexed as

ABAQ, 5-amino-6-hydroxy-8H-benzo[6,7]azepino[5,4,3-de]quinolin-7-oneAOM, azoxymethaneBenzoazepinoqunolinoneColonDextran sodium sulfateDSS, dextran sodium sulfateFenton reactionHCA, heterocyclic amineH&E, hematoxylin and eosinHeterocyclic aminesHigh-grade dysplasiai.g, intragastricInitiationMaillard reactionMeIQx, 2-amino-3,8-dimethylimidazo[4,5-flquinoxalineMicePAH, polycyclic aromatic hydrocarbonsPDCD4PhIP, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Identifiers

PMID28962227
PMCPMC5598209
OpenAlexW2076758525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.