Evidence map›Paper›PMID 28961804›Full record

ArticleThe Journal of infectious diseases2017

Association of Household Food- and Drink-Sharing Practices With Human Herpesvirus 8 Seroconversion in a Cohort of Zambian Children.

Kay L Crabtree, Janet M Wojcicki, Veenu Minhas, Chipepo Kankasa, Charles Mitchell, Charles Wood

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Malignancy and viral infections in Sub-Saharan Africa: A review.Frontiers in virology (Lausanne, Switzerland) · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kay L CrabtreeNebraska Center for Virology and the School of Biological Sciences, University of Nebraska, Lincoln, Nebraska.
Janet M WojcickiDepartment of Pediatrics, University of California, San Francisco.
Veenu MinhasNebraska Center for Virology and the School of Biological Sciences, University of Nebraska, Lincoln, Nebraska.
Chipepo KankasaDepartment of Pediatrics, University Teaching Hospital, University of Zambia, Lusaka, Zambia.
Charles MitchellDepartment of Pediatrics, University of Miami, Florida.
Charles WoodNebraska Center for Virology and the School of Biological Sciences, University of Nebraska, Lincoln, Nebraska.

Funding

Nebraska Center for VirologyP30GM103509 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2012 to 2014
$3.3M
Research Training in Comparative Viral PathogenesisT32AI060547 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI WOOD, CHARLES · 2004 to 2013
$2.5M
NIAID NIH HHS T32 AI060547NIGMS NIH HHS P30 GM103509
6 · The paper itself

Abstract

Background: Human herpesvirus 8 (HHV-8) infection occurs in early childhood and is associated with human immunodeficiency virus type 1 (HIV-1) infection and risk for Kaposi sarcoma, but behaviors associated with HHV-8 transmission are not well described. Methods: We enrolled and followed a prospective cohort of 270 children and their household members to investigate risk factors for HHV-8 transmission in Lusaka, Zambia. Results: We report an incidence of 30.07 seroconversions per 100 child-years. Independent risk factors for HHV-8 incident infection included having a child who shared utensils with a primary caregiver (hazards ratio [HR], 2.33; 95% confidence interval [CI], 1.49-7.14), having an increasing number of HHV-8-infected household members (HR, 1.27; 95% CI, 1.09-2.79), and having ≥5 siblings/children in the household (HR, 2.24; 95% CI, 1.03-4.88). Playing with >5 children a day was protective against infection (HR, 0.54; 95% CI, .33-0.89), as was increasing child age (HR, 0.96; 95% CI, .93-.99). Conclusions: This is the first study to find a temporal association between limited child feeding behaviors and risk for HHV-8 infection. Child food- and drink-sharing behaviors should be included in efforts to minimize HHV-8 transmission, and households with a large number of siblings should receive additional counseling as childhood infections occur in the home context.

Indexed as

Family CharacteristicsFood MicrobiologyBeveragesChild, PreschoolCohort StudiesFemaleHerpesviridae InfectionsHerpesvirus 8, HumanHumansInfantMaleZambiahuman herpesvirus 8Kaposi’s sarcoma–associated herpesviruspremasticationsub-Saharan Africa

Identifiers

PMID28961804
PMCPMC5853242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.