Evidence map›Paper›PMID 28961399›Full record

ArticleACS applied materials & interfaces2017

Active Antioxidizing Particles for On-Demand Pressure-Driven Molecular Release.

Yongbeom Seo, Jiayu Leong, Jye Yng Teo, Jennifer W Mitchell, Martha U Gillette, Bumsoo Han, Jonghwi Lee, Hyunjoon Kong

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Yongbeom SeoDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.
Jiayu LeongDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.
Jye Yng TeoDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.
Jennifer W MitchellDepartment of Cell and Developmental Biology, Neuroscience Program, Beckman Institute for Advanced Science & Technology, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.
Martha U GilletteDepartment of Cell and Developmental Biology, Department of Bioengineering, Neuroscience Program, Beckman Institute for Advanced Science & Technology, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.
Bumsoo HanSchool of Mechanical Engineering, Birck Nanotechnology Center, Purdue Center for Cancer Research, Purdue University , 585 Purdue Mall, West Lafayette, Indiana 47907, United States.
Jonghwi LeeDepartment of Chemical Engineering and Materials Science, Chung-Ang University , Seoul 156-756, South Korea.ORCID http://orcid.org/0000-0003-2336-8695
Hyunjoon KongDepartment of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign , Urbana, Illinois 61801, United States.ORCID http://orcid.org/0000-0003-4680-2968
University of Illinois Urbana-Champaign · USChung-Ang University · KRPurdue University West Lafayette · US

Funding

BRAIN Initiative: Integrated Multimodal Analysis of Cell- and Circuit-Specific Processes in Hippocampal FunctionU01MH109062 · NIMH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SWEEDLER, JONATHAN V. · 2015 to 2017
$2.3M
Nanocells for vascular normalization therapiesR01HL109192 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2011 to 2015
$1.9M
Development of a Liposomal Nanostimulator to Improve Stem Cell-Based Revascularization TherapiesR21HL131469 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI KONG, HYUNJOON · 2016 to 2017
$428k
NHLBI NIH HHS R01 HL109192NHLBI NIH HHS R21 HL131469NIMH NIH HHS U01 MH109062
6 · The paper itself

Abstract

Overproduced reactive oxygen species (ROS) are closely related to various health problems including inflammation, infection, and cancer. Abnormally high ROS levels can cause serious oxidative damage to biomolecules, cells, and tissues. A series of nano- or microsized particles has been developed to reduce the oxidative stress level by delivering antioxidant drugs. However, most systems are often plagued by slow molecular discharge, driven by diffusion. Herein, this study demonstrates the polymeric particles whose internal pressure can increase upon exposure to H

Indexed as

epigallocatechin gallate (EGCG)hydrogen peroxide (H2O2)MnO2 nanosheetsoxidative damagepoly(lactic-co-glycolic acid) (PLGA) particle

Identifiers

PMID28961399
PMCPMC7042956
OpenAlexW2759516632

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.