Evidence map›Paper›PMID 28961382›Full record

ArticleNMR in biomedicine2017

Characterization and stratification of prostate lesions based on comprehensive multiparametric MRI using detailed whole-mount histopathology as a reference standard.

Olga Starobinets, Jeffry P Simko, Kyle Kuchinsky, John Kornak, Peter R Carroll, Kirsten L Greene, John Kurhanewicz, Susan M Noworolski

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Olga StarobinetsDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, USA.ORCID http://orcid.org/0000-0002-6306-1439
Jeffry P SimkoDepartment of Pathology, University of California, San Francisco, USA.
Kyle KuchinskyDepartment of Pathology, University of California, San Francisco, USA.
John KornakDepartment of Epidemiology and Biostatistics, University of California, San Francisco, USA.
Peter R CarrollDepartment of Urology, University of California, San Francisco, USA.
Kirsten L GreeneDepartment of Urology, University of California, San Francisco, USA.
John KurhanewiczDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, USA.
Susan M NoworolskiDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, USA.
University of California, San Francisco · US

Funding

Translation and Evaluation of a Multiparametric Prostate Cancer 3T ExamR01CA137207 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HURD, RALPH EUGENE, KURHANEWICZ, JOHN · 2010 to 2014
$2.6M
DCE MRI to Improve Prostate Cancer Identification and CharacterizationR01CA148708 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NOWOROLSKI, SUSAN M · 2010 to 2014
$1.3M
NCI NIH HHS R01 CA137207NCI NIH HHS R01 CA148708
6 · The paper itself

Abstract

The purpose of this study was to characterize prostate cancer (PCa) based on multiparametric MR (mpMR) measures derived from MRI, diffusion, spectroscopy, and dynamic contrast-enhanced (DCE) MRI, and to validate mpMRI in detecting PCa and predicting PCa aggressiveness by correlating mpMRI findings with whole-mount histopathology. Seventy-eight men with untreated PCa received 3 T mpMR scans prior to radical prostatectomy. Cancerous regions were outlined, graded, and cancer amount estimated on whole-mount histology. Regions of interest were manually drawn on T

Indexed as

AgedHumansLogistic ModelsMagnetic Resonance ImagingMaleMiddle AgedProstateProstatic Neoplasmsdiffusion-weighted imagingdynamic contrast-enhanced imaginghistopathologymagnetic resonance spectroscopy imagingmultiparametric MRIprostate cancer

Identifiers

PMID28961382
PMCPMC9592076
OpenAlexW2759934735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.