Evidence map›Paper›PMID 28961217›Full record

ReviewMolecules (Basel, Switzerland)2017

Non-Covalent Organocatalyzed Domino Reactions Involving Oxindoles: Recent Advances.

Tecla Gasperi, Martina Miceli, Jean-Marc Campagne, Renata Marcia de Figueiredo

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Convenient access to pyrrolidin-3-ylphosphonic acids and tetrahydro-2Beilstein journal of organic chemistry · 2020
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tecla GasperiDipartimento di Scienze, Sezione di Nanoscienze e Nanotecnologie, Università degli Studi Roma Tre, via della Vasca Navale 79, I-00146 Roma, Italy. tecla.gasperi@uniroma3.it.ORCID 0000-0003-3638-2517
Martina MiceliDipartimento di Scienze, Sezione di Nanoscienze e Nanotecnologie, Università degli Studi Roma Tre, via della Vasca Navale 79, I-00146 Roma, Italy. martina.miceli@icloud.com.ORCID 0000-0001-7058-672X
Jean-Marc CampagneICGM-Institut Charles Gerhardt Montpellier, UMR 5253 CNRS-UM-ENSCM, Ecole Nationale Supérieure de Chimie, 8, Rue de l'Ecole Normale, 34296 Montpellier CEDEX 5, France. jean-marc.campagne@enscm.fr.ORCID 0000-0002-4943-047X
Renata Marcia de FigueiredoICGM-Institut Charles Gerhardt Montpellier, UMR 5253 CNRS-UM-ENSCM, Ecole Nationale Supérieure de Chimie, 8, Rue de l'Ecole Normale, 34296 Montpellier CEDEX 5, France. renata.marcia_de_figueiredo@enscm.fr.ORCID 0000-0001-5336-6071

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ubiquitous presence of spirooxindole architectures with several functionalities and stereogenic centers in bioactive molecules has been appealing for the development of novel methodologies seeking their preparation in high yields and selectivities. Expansion and refinement in the field of asymmetric organocatalysis have made possible the development of straightforward strategies that address these two requisites. In this review, we illustrate the current state-of-the-art in the field of spirooxindole synthesis through the use of non-covalent organocatalysis. We aim to provide a concise overview of very recent methods that allow to the isolation of unique, densely and diversified spirocyclic oxindole derivatives with high structural diversity via the use of cascade, tandem and domino processes.

Indexed as

CatalysisChemistry Techniques, SyntheticCinchona AlkaloidsHydrogen BondingIndolesMolecular StructureOxindolesSpiro CompoundsStereoisomerism2-oxindoleCinchona AlkaloidsIndolesOxindolesSpiro Compoundscascadechiral building blocksdominoenantioselectivityhydrogen-bondingnon-covalent organocatalysisspirooxindole derivativestandem

Identifiers

PMID28961217
PMCPMC6151767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.