Evidence map›Paper›PMID 28961215›Full record

ArticleMolecules (Basel, Switzerland)2017

Antibacterial Synthetic Peptides Derived from Bovine Lactoferricin Exhibit Cytotoxic Effect against MDA-MB-468 and MDA-MB-231 Breast Cancer Cell Lines.

Yerly Vargas Casanova, Jorge Antonio Rodríguez Guerra, Yadi Adriana Umaña Pérez, Aura Lucía Leal Castro, Giovanni Almanzar Reina, Javier Eduardo García Castañeda, Zuly Jenny Rivera Monroy

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Biological Activity of Natural and Synthetic Peptides as Anticancer Agents.International journal of molecular sciences · 2024
    Review
  5. Review
  6. Review
  7. Combining the Peptide RWQWRWQWR and an Ethanolic Extract ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Tuna trimmingsCurrent research in food science · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Peptides Derived from (RRWQWRMKKLG)International journal of molecular sciences · 2020
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yerly Vargas CasanovaBiotechnology Institute, Universidad Nacional de Colombia, Carrera 45 No 26-85, 11321 Bogotá, Colombia. yvargasc@unal.edu.co.
Jorge Antonio Rodríguez GuerraPharmacy Department, Universidad Nacional de Colombia, Carrera 45 No 26-85, Building 450, Office 213, 11321 Bogotá, Colombia. jorarodriguezg@unal.edu.co.
Yadi Adriana Umaña PérezChemistry Department, Universidad Nacional de Colombia, Carrera 45 No 26-85, Building 450, Office 213, 11321 Bogotá, Colombia. jaumanap@unal.edu.co.
Aura Lucía Leal CastroMedicine Faculty, Universidad Nacional de Colombia, Carrera 45 No 26-85, Building 450, Office 213, 11321 Bogotá, Colombia. allealc@unal.edu.co.
Giovanni Almanzar ReinaUniversity Children's Hospital, University of Wurzburg, 97080 Wurzburg, Germany. Almanzar_G@ukw.de.
Javier Eduardo García CastañedaPharmacy Department, Universidad Nacional de Colombia, Carrera 45 No 26-85, Building 450, Office 213, 11321 Bogotá, Colombia. jaegarciac@unal.edu.co.
Zuly Jenny Rivera MonroyChemistry Department, Universidad Nacional de Colombia, Carrera 45 No 26-85, Building 450, Office 213, 11321 Bogotá, Colombia. zjriveram@unal.edu.co.
Universidad Nacional de Colombia · COUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin B, containing the RRWQWR motif, were designed, synthesized, purified, and characterized using RP-HPLC chromatography and MALDI-TOF mass spectrometry. The antibacterial activity of the designed peptides against

Indexed as

Amino Acid SequenceAnimalsAnti-Bacterial AgentsAntineoplastic AgentsApoptosisBacteriaBreast NeoplasmsCattleCell Line, TumorCell ProliferationChromatography, High Pressure LiquidDose-Response Relationship, DrugFemaleHumansLactoferrinMass SpectrometryAnti-Bacterial AgentsAntineoplastic Agentslactoferricin BLactoferrinPeptidesantibacterial activitybreast cancercytotoxic effectE. colilactoferricin Bsynthetic peptides

Identifiers

PMID28961215
PMCPMC6151437
OpenAlexW2760329750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.