ArticleIEEE transactions on bio-medical engineering2018
MRI-Guided Robotically Assisted Focal Laser Ablation of the Prostate Using Canine Cadavers.
Article in IEEE transactions on bio-medical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- MRI Robots for Needle-Based Interventions: Systems and Technology.Annals of biomedical engineering · 2018Pooled it
- Development of a Low-Profile, Piezoelectric Robot for MR-Guided Abdominal Needle Interventions.Annals of biomedical engineering · 2025Article
- Body-Mounted MR-Conditional Robot for Minimally Invasive Liver Intervention.Annals of biomedical engineering · 2024Article
- MR-Safe Cartesian Platform for Active Cardiac Shimming: Preliminary Validation.IEEE transactions on bio-medical engineering · 2024Article
- Automatic segmentation of prostate and extracapsular structures in MRI to predict needle deflection in percutaneous prostate intervention.International journal of computer assisted radiology and surgery · 2023Article
- HoloLens augmented reality system for transperineal free-hand prostate procedures.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Flexible Needle Bending Model for Spinal Injection Procedures.IEEE robotics and automation letters · 2023Article
- Towards catheter steering using magnetic tractor beam coupling.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2022Article
- MR-Conditional Actuations: A Review.Annals of biomedical engineering · 2020Review
- Design of a 6-DoF Parallel Robotic Platform for MRI Applications.Journal of medical robotics researchArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectivea magnetic resonance imaging (MRI)-conditional needle guidance robot is developed to enhance MRI-guided focal laser ablation (FLA) therapy in patients with focal prostate cancer.
methodsinspired by the workflow of the manual FLA therapy, we developed an MRI-conditional robot with two degrees of freedom to provide the guidance for laser ablation catheter. This robot is powered by pneumatic turbine motors and encoded with the custom-designed optical encoder. The needle could be inserted manually through the designed robotic system, which keeps the patients inside MRI bore throughout the procedure. The robot hardware is integrated with the custom ablation planning and monitoring software (OncoNav) to provide an iterative treatment plan to cover the whole ablation zone. Virtual tumors were selected in three canine cadavers as targets to validate the performance of the proposed hardware and software system.
resultsphantom studies show that the average targeting error is less than 2 mm and the workflow of the entire procedure lasts for 100 minutes. Canine cadaver experiment results show that all the targets were successfully ablated in no more than three administrations. SIGNIFICANCE: MRI-guided prostate FLA is feasible using the proposed hardware and software system, indicating potential utility in future human trials.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.