ArticleMolecular plant pathology2018
The feruloyl esterase genes are required for full pathogenicity of the apple tree canker pathogen Valsa mali.
Article in Molecular plant pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 43 citations in OpenAlex.
- Identification, Subcellular Localization, and Infection-Related Expression of a Novel Haloacid Dehalogenase Gene (Journal of fungi (Basel, Switzerland) · 2025Article
- Study on Pathogenesis ofJournal of fungi (Basel, Switzerland) · 2025Article
- Adaptive regulation of miRNAs/milRNAs in tissue-specific interaction between apple andHorticulture research · 2024Article
- A Glycosyl Hydrolase 5 Family Protein Is Essential for Virulence of Necrotrophic Fungi and Can Suppress Plant Immunity.International journal of molecular sciences · 2024Article
- The secreted feruloyl esterase of Verticillium dahliae modulates host immunity via degradation of GhDFR.Molecular plant pathology · 2024Article
- Xylanase VmXyl2 is involved in the pathogenicity ofFrontiers in plant science · 2024Article
- Antifungal Activity of 6-Methylcoumarin againstJournal of fungi (Basel, Switzerland) · 2022Article
- The apple FERONIA receptor-like kinase MdMRLK2 negatively regulates Valsa canker resistance by suppressing defence responses and hypersensitive reaction.Molecular plant pathology · 2022Article
- Feruloyl esterase Fae1 is required specifically for host colonisation by the rice-blast fungus Magnaporthe oryzae.Current genetics · 2022Article
- The Transcription FactorFrontiers in microbiology · 2022Article
- Comparative Analysis of Herbaceous and Woody Cell Wall Digestibility by Pathogenic Fungi.Molecules (Basel, Switzerland) · 2021Article
- Hydroxybenzoate hydroxylase genes underlying protocatechuic acid production in Valsa mali are required for full pathogenicity in apple trees.Molecular plant pathology · 2021Article
- The Role of Glycoside Hydrolases in Phytopathogenic Fungi and Oomycetes Virulence.International journal of molecular sciences · 2021Review
- Diversity and Biocontrol Potential of Cultivable Endophytic Bacteria Associated with Halophytes from the West Aral Sea Basin.Microorganisms · 2021Article
- Host Cell Wall Damage during Pathogen Infection: Mechanisms of Perception and Role in Plant-Pathogen Interactions.Plants (Basel, Switzerland) · 2021Review
- Vm-milR37 contributes to pathogenicity by regulating glutathione peroxidase gene VmGP in Valsa mali.Molecular plant pathology · 2021Article
- Draft genomes of non-nitrogen-fixingJournal of genomics · 2021Article
- β-GlucosidaseFrontiers in microbiology · 2021Article
- A specific fungal transcription factor controls effector gene expression and orchestrates the establishment of the necrotrophic pathogen lifestyle on wheat.Scientific reports · 2019Article
- Latent Infection of Valsa mali in the Seeds, Seedlings and Twigs of Crabapple and Apple Trees is a Potential Inoculum Source of Valsa Canker.Scientific reports · 2019Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apple Valsa canker, caused by the fungus Valsa mali, is one of the most destructive diseases of apple trees in East Asia. Feruloyl esterases (ferulic acid esterases, FAEs), which belong to a subclass of carboxylic esterases, can cleave ester bonds that crosslink hydroxycinnamic acids and arabinoxylans or certain pectins in plant cell walls. However, a pathogenic role of FAE has not been demonstrated in plant-pathogenic fungi. In this study, the FAE gene family, including one type A, one type B, three type C and two type D FAE genes, was identified in V. mali. Five of the seven FAE genes had highly elevated transcript levels in V. mali-apple tree bark interactions compared with mycelia grown in axenic culture. Signal peptides of the VmFAEs were confirmed using yeast signal sequence trap assays. To examine whether FAEs are required for the pathogenicity of V. mali, seven single- and six double-gene deletion mutants were generated. Compared with the wild-type, three of the seven FAE single-deletion mutants showed significantly reduced pathogenicity and three of the six FAE double-deletion mutants exhibited greater reductions in pathogenicity, suggesting the joint action of FAEs in the V. mali-apple tree interaction. Most of the FAE mutants that exhibited a significant reduction in pathogenicity had significantly lower FAE activity than the wild-type fungus. These results indicate that secreted FAEs are required for the full pathogenicity of the phytopathogenic fungus V. mali.
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