Evidence map›Paper›PMID 28960691›Full record

ArticleProtein science : a publication of the Protein Society2018

Web-accessible molecular modeling with Rosetta: The Rosetta Online Server that Includes Everyone (ROSIE).

Rocco Moretti, Sergey Lyskov, Rhiju Das, Jens Meiler, Jeffrey J Gray

Abstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Unraveling the Glycosylation Machinery ofInternational journal of molecular sciences · 2026
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  7. Article
  8. Article
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  12. Protein-Protein Docking Approach to GPCR Oligomerization.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Recent Advances in NMR Protein Structure Prediction with ROSETTA.International journal of molecular sciences · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rocco MorettiDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee.
Sergey LyskovDepartment of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland.
Rhiju DasDepartment of Biochemistry, Stanford University, Stanford, California.
Jens MeilerDepartment of Chemistry, Vanderbilt University, Nashville, Tennessee.
Jeffrey J GrayDepartment of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland.ORCID 0000-0001-6380-2324

Funding

ROSETTA An Integrated Protein Structure Modeling SuiteR01GM073151 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KUHLMAN, BRIAN A · 2005 to 2019
$7.8M
Next-generation computational/chemical methods for complex RNA structuresR35GM122579 · NIGMS · STANFORD UNIVERSITY · PI Rhiju Das · 2017 to 2026
$7.2M
Prediction of the Structure of Therapeutic Antibodies with their AntigensR01GM078221 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GRAY, JEFFREY J · 2006 to 2020
$4.0M
High-Performance Computer Cluster for Biomedical ResearchS10OD023680 · OD · VANDERBILT UNIVERSITY · PI MEILER, JENS · 2017 to 2017
$587k
GPU-Accelerated Parallel Computer for Drug Discovery ApplicationsS10OD020154 · OD · VANDERBILT UNIVERSITY · PI SMITH, JARROD ANSON · 2015 to 2015
$225k
NIGMS NIH HHS R01 GM073151NIGMS NIH HHS R01 GM078221NIGMS NIH HHS R35 GM122579NIH HHS S10 OD023680
6 · The paper itself

Abstract

The Rosetta molecular modeling software package provides a large number of experimentally validated tools for modeling and designing proteins, nucleic acids, and other biopolymers, with new protocols being added continually. While freely available to academic users, external usage is limited by the need for expertise in the Unix command line environment. To make Rosetta protocols available to a wider audience, we previously created a web server called Rosetta Online Server that Includes Everyone (ROSIE), which provides a common environment for hosting web-accessible Rosetta protocols. Here we describe a simplification of the ROSIE protocol specification format, one that permits easier implementation of Rosetta protocols. Whereas the previous format required creating multiple separate files in different locations, the new format allows specification of the protocol in a single file. This new, simplified protocol specification has more than doubled the number of Rosetta protocols available under ROSIE. These new applications include pK

Indexed as

InternetMolecular Docking SimulationSoftwarePeptidesProteinsPeptidesProteinsdesignmolecular modelingpredictionweb server

Identifiers

PMID28960691
PMCPMC5734271

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.