ArticleProteins2018
Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
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Article in Proteins, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10citing papers in PubMed
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Who cites it
10 citing papers in PubMed.
- Article
- Functional Relevance of CASP16 Nucleic Acid Predictions as Evaluated by Structure Providers.Proteins · 2026Article
- Functional relevance of CASP16 nucleic acid predictions as evaluated by structure providers.bioRxiv : the preprint server for biology · 2025Article
- RNA target highlights in CASP15: Evaluation of predicted models by structure providers.Proteins · 2023Article
- Metagenome diversity illuminates origins of pathogen effectors.bioRxiv : the preprint server for biology · 2023Article
- Cryptic Genes for Interbacterial Antagonism DistinguishFrontiers in cellular and infection microbiology · 2022Article
- Article
- Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.Structure (London, England : 1993) · 2021Article
- Flexible Backbone Assembly and Refinement of Symmetrical Homomeric Complexes.Structure (London, England : 1993) · 2019Article
- Article
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Authors and funding
39 authors.
Andriy KryshtafovychGenome Center, University of California, Davis, 451 Health Sciences Drive, Davis, California, 95616.ORCID 0000-0001-5066-7178
Reinhard AlbrechtDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.
Arnaud BasléInstitute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne NE2 4HH, United Kingdom.
Pedro BuleCIISA - Faculdade de Medicina Veterinária, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477, Portugal, Lisboa.ORCID 0000-0003-2531-9926
Alessandro T CaputoOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, England, United Kingdom.ORCID 0000-0001-5007-6896
Ana Luisa CarvalhoUCIBIO, REQUIMTE, Departamento de Química, Faculdade de Cien⁁cias e Tecnologia, Universidade Nova de Lisboa, Caparica, 2829-516, Portugal.ORCID 0000-0002-3824-0240
Kinlin L ChaoInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, 20850.
Ron DiskinDepartment of Structural Biology, Weizmann Institute of Science, Rehovot, Israel.
Krzysztof FidelisGenome Center, University of California, Davis, 451 Health Sciences Drive, Davis, California, 95616.ORCID 0000-0002-8061-412X
Carlos M G A FontesCIISA - Faculdade de Medicina Veterinária, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477, Portugal, Lisboa.ORCID 0000-0002-1219-9753
Folmer FredslundDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen Ø, Denmark.
Harry J GilbertInstitute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne NE2 4HH, United Kingdom.ORCID 0000-0003-3597-2347
Celia W GouldingDepartment of Molecular Biology and Biochemistry/Pharmaceutical Sciences, University of California Irvine, Irvine, California, 92697.
Marcus D HartmannDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Tübingen, 72076, Germany.ORCID 0000-0001-6937-5677
Christopher S HayesDepartment of Molecular, Cellular and Developmental Biology/Biomolecular Science and Engineering Program, University of California, Santa Barbara, Santa Barbara, California, 93106.
Osnat HerzbergInstitute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland, 20850.
Johan C HillOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, England, United Kingdom.
Andrzej JoachimiakArgonne National Laboratory, Midwest Center for Structural Genomics/Structural Biology Center, Biosciences Division, Argonne, Illinois, 60439.
Gert-Wieland KohringMicrobiology, Saarland University, Campus Building A1.5, Saarbrücken, Saarland, D-66123, Germany.
Roman I KoningNetherlands Centre for Electron Nanoscopy, Institute of Biology Leiden, Leiden University, 2333, CC Leiden, The Netherlands.ORCID 0000-0001-6736-7147
Leila Lo LeggioDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100 Copenhagen Ø, Denmark.ORCID 0000-0002-5135-0882
Marco MangiagalliDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, 20126, Italy.ORCID 0000-0001-8211-165X
Karolina MichalskaArgonne National Laboratory, Midwest Center for Structural Genomics/Structural Biology Center, Biosciences Division, Argonne, Illinois, 60439.
John MoultDepartment of Cell Biology and Molecular genetics, University of Maryland, 9600 Gudelsky Drive, Institute for Bioscience and Biotechnology Research, Rockville, Maryland, 20850.ORCID 0000-0002-3012-2282
Shabir NajmudinCIISA - Faculdade de Medicina Veterinária, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477, Portugal, Lisboa.ORCID 0000-0002-0429-5454
Marco NardiniDepartment of Biosciences, University of Milano, Milano, 20133, Italy.ORCID 0000-0002-3718-2165
Valentina NardoneDepartment of Biosciences, University of Milano, Milano, 20133, Italy.ORCID 0000-0003-3729-0200
Didier NdehInstitute for Cell and Molecular Biosciences, University of Newcastle, Newcastle upon Tyne NE2 4HH, United Kingdom.
Thanh-Hong NguyenDepartment of Macromolecular Structures, Centro Nacional de Biotecnologia (CSIC), calle Darwin 3, Madrid, 28049, Spain.ORCID 0000-0002-7079-4200
Guido PintacudaUniversité de Lyon, Centre de RMN à Très Hauts Champs, Institut des Sciences Analytiques (UMR 5280 - CNRS, ENS Lyon, UCB Lyon 1), Villeurbanne, 69100, France.
Sandra PostelUniversity of Maryland School of Medicine, Institute of Human Virology, Baltimore, Maryland, 21201.ORCID 0000-0002-6717-1870
Mark J van RaaijDepartment of Macromolecular Structures, Centro Nacional de Biotecnologia (CSIC), calle Darwin 3, Madrid, 28049, Spain.ORCID 0000-0002-4781-1375
Pietro RoversiOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, England, United Kingdom.ORCID 0000-0001-9280-9437
Amir ShimonDepartment of Structural Biology, Weizmann Institute of Science, Rehovot, Israel.
Abhimanyu K SinghSchool of Biosciences, University of Kent, Canterbury, Kent, CT2 7NJ, United Kingdom.ORCID 0000-0002-9998-020X
Eric J SundbergDepartment of Medicine and Department of Microbiology and Immunology, University of Maryland School of Medicine, Institute of Human Virology, Baltimore, Maryland, 21201.ORCID 0000-0003-0478-3033
Kaspars TarsLatvian Biomedical Research and Study Center, Rātsupītes 1, Riga, LV1067, Latvia.
Nicole ZitzmannOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, England, United Kingdom.
Torsten SchwedeBiozentrum/SIB Swiss Institute of Bioinformatics, Klingelbergstrasse 50, Basel, 4056, Switzerland.ORCID 0000-0003-2715-335X
Funding
Midwest Center for Structural GenomicsU54GM094585 · NIGMS · UNIVERSITY OF CHICAGO · PI OTWINOWSKI, ZBYSZEK · 2010 to 2014
$33.7MProspective analysis to determine model accuracy performance and boundaries in the post-AlphaFold2 environmentR01GM100482 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIDELIS, KRZYSZTOF A · 2012 to 2025
$11.1MThe Midwest Center for Structural Genomics - Community ResourceR24GM115586 · NIGMS · UNIVERSITY OF CHICAGO · PI JOACHIMIAK, ANDRZEJ · 2015 to 2017
$2.8MStructure-function analysis of polymorphic CDI toxin-immunity protein complexes aU01GM102318 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GOULDING, CELIA · 2012 to 2016
$1.7MMolecular mechanisms of antibacterial CDI toxin activationR01GM117373 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOULDING, CELIA, HAYES, CHRISTOPHER S. · 2016 to 2019
$1.2MIdentification and in vitro experimental investigation of missense SNPs implicateR01GM102810 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI HERZBERG, OSNAT, MOULT, JOHN · 2012 to 2015
$1.1MNIGMS NIH HHS R01 GM100482NIGMS NIH HHS R01 GM102810NIGMS NIH HHS R01 GM117373NIGMS NIH HHS R24 GM115586NIGMS NIH HHS U01 GM102318NIGMS NIH HHS U54 GM094585Wellcome TrustWellcome Trust 097300/Z/11/ZWellcome Trust 106272/Z/14/Z
Abstract
The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP12 experiment.
Indexed as
Models, MolecularProtein ConformationAnimalsBacteriaComputational BiologyCrystallography, X-RayHumansProtein FoldingProteinsSoftwareProteinsCASPNMRprotein structure predictionX-ray crystallography
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