Evidence map›Paper›PMID 28960466›Full record

ArticleJournal of veterinary internal medicine2017

Chronic Gingivostomatitis with Esophagitis in Cats.

M I Kouki, S A Papadimitriou, D Psalla, A Kolokotronis, T S Rallis

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. 2025 FelineVMA feline oral health and dental care guidelines.Journal of feline medicine and surgery · 2025
    Guideline
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  10. An Update on Feline Chronic Gingivostomatitis.The Veterinary clinics of North America. Small animal practice · 2020
    Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M I KoukiCompanion Animal Clinic, Surgery and Obstetrics Unit, School of Veterinary Medicine, Aristotle University, Thessaloniki, Greece.
S A PapadimitriouCompanion Animal Clinic, Surgery and Obstetrics Unit, School of Veterinary Medicine, Aristotle University, Thessaloniki, Greece.ORCID http://orcid.org/0000-0001-7956-501X
D PsallaLaboratory of Pathology, School of Veterinary Medicine, Aristotle University, Thessaloniki, Greece.
A KolokotronisDepartment of Oral Medicine and Oral Pathology, School of Dentistry, Aristotle University, Thessaloniki, Greece.
T S RallisCompanion Animal Clinic, Internal Medicine Unit, School of Veterinary Medicine, Aristotle University, Thessaloniki, Greece.
Aristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic gingivostomatitis in cats (FCG) is a debilitating disease with potentially deleterious effects on overall health. HYPOTHESIS/

objectivesLittle is known about the pathophysiology and overall impact of FCG. The aims of our study were to investigate whether gingivostomatitis occurs concurrently with esophagitis, if FCG treatment contributes to esophagitis and if esophagitis exacerbates signs of FCG. ANIMALS: Fifty-eight cats with clinical signs of FCG and 12 healthy control cats exhibiting no signs of oral disease, all client-owned.

methodsProspective study. Physical, oral and endoscopic examinations were performed on all cats. Measurements of salivary and esophageal lumen pH were obtained from both groups. Biopsies were acquired from sites of esophageal inflammation in cats with FCG and from normal-appearing esophageal mucosa in control cats.

resultsThe majority of cats with clinical signs of FCG exhibited some degree of esophagitis especially in the proximal (44/58) and distal (53/58) parts (P < 0.001) with or without columnar metaplasia, compared to controls. All cats lacked signs related to gastrointestinal disease. Salivary and esophageal lumen pH were not statistically different compared to controls. CONCLUSIONS AND CLINICAL IMPORTANCE: Feline chronic gingivostomatitis seems to occur concurrently with esophagitis. Esophagitis also should be managed in cats with chronic gingivostomatitis because it may aggravate the existing condition.

Indexed as

AnimalsBiopsyCase-Control StudiesCat DiseasesCatsEsophagitisFemaleGingivitisHydrogen-Ion ConcentrationMaleProspective StudiesSalivaStomatitisCatEsophageal metaplasiaEsophagitisOral mucosa inflammation

Identifiers

PMID28960466
PMCPMC5697197
OpenAlexW2757830129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.