Evidence map›Paper›PMID 28960336›Full record

SynthesisAllergy2018

The prevalence of atopic dermatitis beyond childhood: A systematic review and meta-analysis of longitudinal studies.

K Abuabara, A M Yu, J-P Okhovat, I E Allen, S M Langan

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 12 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 12 syntheses or guidelines pooled it, 220 citations in OpenAlex.

  1. Topical anti-inflammatory treatments for eczema: network meta-analysis.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Pooled it
  3. Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Phototherapy for atopic eczema.The Cochrane database of systematic reviews · 2021
    Pooled it
  7. Pooled it
  8. Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2021
    Pooled it
  9. Pooled it
  10. Probiotics for treating eczema.The Cochrane database of systematic reviews · 2018
    Pooled it
  11. Pooled it
  12. Pooled it
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Article
  19. Atopic dermatitis is associated with herpes zoster in adults - A matched cohort study using electronic health records data in England.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Article
  20. Review

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

K AbuabaraProgram for Clinical Research, Department of Dermatology, University of California San Francisco (UCSF), San Francisco, CA, USA.ORCID 0000-0002-7736-6946
A M YuFaculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
J-P OkhovatHarvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA, USA.
I E AllenDepartment of Epidemiology and Biostatistics, University of California San Francisco (UCSF), San Francisco, CA, USA.
S M LanganFaculty of Epidemiology & Population Health, London School of Hygiene and Tropical Medicine, London, UK.
University of California, San Francisco · USBeth Israel Deaconess Medical Center · USLondon School of Hygiene & Tropical Medicine · GBUniversity of Ottawa · CA

Funding

Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
NCATS NIH HHS KL2 TR000143Wellcome Trust 205039/Z/16/Z
6 · The paper itself

Abstract

backgroundThere are sparse and conflicting data regarding the long-term clinical course of atopic dermatitis (AD). Although often described as a childhood disease, newer population-based estimates suggest the prevalence of pediatric and adult disease may be similar.

methodsOur objective was to determine whether there is a decline in the prevalence of AD in population-based cohorts of patients followed longitudinally beyond childhood. We conducted a systematic review and meta-analysis including studies assessing AD prevalence across 3 or more points in time. The primary outcome was weighted overall risk difference (percentage decrease in AD prevalence).

resultsOf 2080 references reviewed, 7 studies with 13 515 participants were included. Participants were assessed at 3-6 time points, ranging from age 3 months to 26 years. The percentage decrease in prevalence after age 12 was 1%, which was not significantly different from zero (95% confidence interval -2%-5%). Similar results were found with other age cut-offs.

conclusionThe prevalence of AD in longitudinal birth cohort studies is similar in childhood and adolescence/early adulthood.

Indexed as

AdolescentAdultChildChild, PreschoolDermatitis, AtopicFemaleHumansInfantLongitudinal StudiesMalePrevalenceYoung Adultatopic dermatitisatopic eczemaeczemanatural historyprevalence

Identifiers

PMID28960336
PMCPMC5830308
OpenAlexW2759745678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.