Evidence map›Paper›PMID 28960202›Full record

ArticleNature cell biology2017

Myofibrils put the squeeze on nuclei.

Jonathan N Rosen, Mary K Baylies

Abstract read
In one paragraph

Article in Nature cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects of mutant lamins on nucleo-cytoskeletal coupling inFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jonathan N RosenProgram in Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.
Mary K BayliesProgram in Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Mechanisms and Function of Myonuclear PositioningR01AR068128 · NIAMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2014 to 2025
$5.1M
Mechanisms Regulating Myoblast Fusion in DrosophilaR01GM078318 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2007 to 2010
$2.0M
Sizing and Scaling in Functional Muscle CellsR01GM121971 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI BAYLIES, MARY K · 2017 to 2020
$1.8M
NCI NIH HHS P30 CA008748NIAMS NIH HHS R01 AR068128NIGMS NIH HHS R01 GM078318NIGMS NIH HHS R01 GM121971
6 · The paper itself

Abstract

During muscle development, nuclei travel from the centre of the myofibre to the periphery, a process defective in certain diseases. A new study reveals that this movement is due to centripetal forces imposed on nuclei by the crosslinking and contraction of myofibrils.

Indexed as

Muscle ContractionMyofibrilsCell NucleusHumansMovement

Identifiers

PMID28960202
PMCPMC5933531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.