ArticleCurrent medical mycology2016
Clinical features, diagnosis, and outcomes of rhino-orbito-cerebral mucormycosis- A retrospective analysis.
Article in Current medical mycology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Clinical Features and Surgical Outcomes in Patients With Central Skull Base Osteomyelitis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- Recent Trend of Surge in Pulmonary involvement in Sinonasal Mucormycosis: A Case Series: Pulmonary involvement in Sinonasal Mucormycosis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Management challenges of postpartum rhinocerebral mucormycosis following spontaneous vaginal delivery in a resource-constraint setting: A case report and review of literature.International journal of surgery case reports · 2025Article
- Estimation of the pattern of ocular manifestations, risk factors, and imaging of rhino-orbital-cerebral mucormycosis in COVID-19 patients.Journal of family medicine and primary care · 2025Article
- The first report of rhinosinusitis by Rhizopus delemar in a patient with severe COVID-19 in Iran: a case report.Journal of medical case reports · 2024Article
- Prognostic factors and clinical features of rhino-orbital-mucormycosis cases: an update for patient and visual survivals.International journal of ophthalmology · 2024Article
- The Study of Clinical Profile of Patients With Mucormycosis During COVID-19 Pandemic in Tertiary Care Hospital.Cureus · 2023Article
- A case report of brainstem hemorrhage due to Rhizopus delemar-induced encephalitis diagnosed by metagenomic next-generation sequencing (mNGS).BMC infectious diseases · 2023Article
- Article
- Rhino-orbito-cerebral Mucormycosis: Etiopathology, Clinical Features, Outcome, and the Factors Associated with Outcome.Korean journal of ophthalmology : KJO · 2022Article
- Mucormycosis in COVID-19 pandemic: study at tertiary hospital in India.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Bilateral blindness in a young male of rhino-orbital-cerebral mucormycosis: A case report.Indian journal of ophthalmology · 2022Article
- Rhino-orbito-cerebral mucormycosis during the COVID-19 third wave in 2021: an Egyptian preliminary report from a single tertiary hospital.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Successful treatment of rhino-cerebral mucormycosis with dual antifungal therapy and minimal surgical debridement.IDCases · 2022Article
- Clinical outcome of orbital apex syndrome in COVID associated mucormycosis patients in a tertiary care hospital.International journal of ophthalmology · 2022Article
- Rhino-Orbital-Cerebral Mucormycosis: A Rare Complication of Uncontrolled Diabetes.Case reports in surgery · 2022Article
- COVID-19 Associated Mucormycosis: A Systematic Review from Diagnostic Challenges to Management.Diseases (Basel, Switzerland) · 2021Review
- Mucormycosis: An unanticipated progeny of COVID-19.JNMA; journal of the Nepal Medical Association · 2021Article
- Second wave of COVID-19 pandemic and the surge of mucormycosis: Lessons learnt and future preparedness: Indian Society of Anaesthesiologists (ISA National) Advisory and Position Statement.Indian journal of anaesthesia · 2021Article
- Rhino-orbital cerebral mucormycosis in a child with type 1 diabetes: A case report.SAGE open medical case reports · 2021Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeRhino-orbito-cerebral mucormycosis (ROCM) is a rare disease with acute and fulminant manifestation. This infection is associated with high morbidity and mortality rates. Herein, we reviewed the manifestations, underlying conditions, medical treatments, and surgical interventions in ROCM patients admitted to a tertiary referral center in northern Iran over a seven-year period. MATERIALS AND
methodsIn a retrospective analysis, 15 cases of ROCM were identified from 2007 to 2013 in Bu Ali Sina Hospital, Sari, Iran. All the ROCM cases were clinically diagnosed and confirmed by histopathological and/or mycological examination. The relevant demographic data, clinical, ophthalmic, and neurologic manifestations, underlying conditions, medical treatments, and surgical interventions were recorded and analyzed.
resultsThe mean age of the patients was 54±11 years (age range: 28-70 years); 26.7% of the patients were male and 73.3% female (male: female ratio of 1: 2.7). Uncontrolled diabetes was noted in at least 86.7% (13/15) of the cases. The maxillary sinuses were the most frequently involved sites (66.7% of the cases) followed by the ethmoid sinus. Amphotericin B in combination with surgical debridement was used in the treatment of 80% of the cases. Furthermore, 73.3% of the patients who were diagnosed early and underwent medical and extensive surgical debridement of the infected tissues survived.
conclusionUncontrolled diabetes mellitus is considered to be the main predisposing factor for ROCM. To prevent and reduce mortality rate of this acute disease, early diagnosis based on clinical findings and biopsy is recommended.
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