Evidence map›Paper›PMID 28959700›Full record

ArticleOpen forum infectious diseases2017

Advanced Human Immunodeficiency Virus Disease at Diagnosis in Mozambique and Swaziland.

Stephanie A Kujawski, Matthew R Lamb, Maria Lahuerta, Margaret L McNairy, Laurence Ahoua, Fatima Abacassamo, Harriet Nuwagaba-Biribonwoha, Averie Gachuhi, Wafaa M El-Sadr, Batya Elul

Erratum issuedAbstract read
In one paragraph

Article in Open forum infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Reduction in Baseline CD4 Count Testing Following Human Immunodeficiency Virus "Treat All" Adoption in Uganda.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Persistent Challenge of Advanced HIV Disease and AIDS in the Era of Antiretroviral Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Stephanie A KujawskiDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.
Matthew R LambDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.
Maria LahuertaDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.
Margaret L McNairyWeill Cornell Medical College, New York, New York.
Laurence AhouaICAP at Columbia University Mailman School of Public Health, New York, New York.
Fatima AbacassamoCentro de Colaboração em Saude, Maputo, Mozambique.
Harriet Nuwagaba-BiribonwohaDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.
Averie GachuhiICAP at Columbia University Mailman School of Public Health, New York, New York.
Wafaa M El-SadrDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.
Batya ElulDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York.

Funding

Global HIV Implementation Science Research Training Grant RenewalT32AI114398 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Yael R Hirsch-Moverman · 2014 to 2026
$4.1M
LINK4HEALTH: A Combination Strategy for Linkage and Retention, SwazilandR01AI100059 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EL-SADR, WAFAA M. · 2012 to 2014
$3.3M
NIAID NIH HHS R01 AI100059NIAID NIH HHS T32 AI114398
6 · The paper itself

Abstract

backgroundEarly diagnosis of human immunodeficiency virus (HIV) is a prerequisite to maximizing individual and societal benefits of antiretroviral therapy.

methodsAdults ≥18 years of age testing HIV positive at 10 health facilities in Mozambique and Swaziland received point-of-care CD4

resultsAmong 2333 participants, the median CD4

conclusionsMore than 10 years into the global scale up of comprehensive HIV services, the majority of adults diagnosed with HIV at health facilities in 2 high-prevalence countries presented with advanced disease and 1 in 7 had severe immunosuppression. Innovative strategies for early identification of HIV-positive individuals are urgently needed.

Indexed as

advanced HIV diseaselate diagnosispoint-of-care CD4 testingsub-Saharan Africa

Identifiers

PMID28959700
PMCPMC5610724

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.