Evidence map›Paper›PMID 28959690›Full record

ArticleVeterinary sciences2016

Tick-Borne Relapsing Fever Spirochetes in the Americas.

Job E Lopez, Aparna Krishnavahjala, Melissa N Garcia, Sergio Bermudez

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Human Exposure to Spirochete-InfectedOpen forum infectious diseases · 2026
    Article
  3. Article
  4. Article
  5. Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Autogenous reproduction byApplied and environmental microbiology · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Molecular evidence ofFrontiers in veterinary science · 2023
    Article
  14. IsTropical medicine and infectious disease · 2022
    Article
  15. Tick species infesting humans in the United States.Ticks and tick-borne diseases · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Job E LopezDepartment of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, 77030 TX, USA.
Aparna KrishnavahjalaDepartment of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, 77030 TX, USA.
Melissa N GarciaDepartment of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine, Houston, 77030 TX, USA.
Sergio BermudezDepartamento de Investigación en Entomología Médica, Instituto Conmemorativo Gorgas de Estudios de la Salud, P.O. Box 816-02593, City of Panama, Panama.
Baylor College of Medicine · USInstituto Conmemorativo Gorgas de Estudios de la Salud · PA

Funding

Relapsing Fever Spirochete Protein Production within the VectorR21AI103724 · NIAID · MISSISSIPPI STATE UNIVERSITY · PI LOPEZ, JOB E · 2013 to 2014
$363k
Understanding the ecology of tick-borne relapsing fever spirochetes in PanamaR03AI123652 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI LOPEZ, JOB E · 2016 to 2017
$159k
NIAID NIH HHS R03 AI123652NIAID NIH HHS R21 AI103724
6 · The paper itself

Abstract

Relapsing fever spirochetes are tick- and louse-borne pathogens that primarily afflict those in impoverished countries. Historically the pathogens have had a significant impact on public health, yet currently they are often overlooked because of the nonspecific display of disease. In this review, we discuss aspects of relapsing fever (RF) spirochete pathogenesis including the: (1) clinical manifestation of disease; (2) ability to diagnose pathogen exposure; (3) the pathogen's life cycle in the tick and mammal; and (4) ecological factors contributing to the maintenance of RF spirochetes in nature.

Indexed as

argasidBorreliaixodidOrnithodorosrelapsing fever spirochetes

Identifiers

PMID28959690
PMCPMC5606572
OpenAlexW2514573950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.