ArticleFrontiers in pediatrics2017
Treatment Strategies for Congenital Diaphragmatic Hernia: Change Sometimes Comes Bearing Gifts.
Article in Frontiers in pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Congenital Diaphragmatic Hernia - Is there a sex specific severity phenotype?European journal of pediatrics · 2025Pooled it
- Impact of fetal treatments for congenital diaphragmatic hernia on lung development.Anatomical record (Hoboken, N.J. : 2007) · 2025Review
- Late diagnosis of congenital diaphragmatic hernia: a case report.Journal of medical case reports · 2023Article
- Lung Ultrasound Score in Neonates with Congenital Diaphragmatic Hernia (CDH-LUS): A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2023Article
- Early vasopressin infusion improves oxygenation in infants with congenital diaphragmatic hernia.Frontiers in pediatrics · 2023Article
- Article
- ECMO utilization in infants with congenital diaphragmatic hernia in the USA.World journal of pediatric surgery · 2022Article
- Unsolved problems in CDH follow-up.Frontiers in pediatrics · 2022Article
- Perinatal stabilisation of infants born with congenital diaphragmatic hernia: a review of current concepts.Archives of disease in childhood. Fetal and neonatal edition · 2020Review
- Congenital diaphragmatic hernia: a scientometric analysis of the global research activity and collaborative networks.Pediatric surgery international · 2018Review
- Congenital diaphragmatic hernia: 25 years of shared knowledge; what about survival?Jornal de pediatriaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo report treatment strategies' evolution and its impact on congenital diaphragmatic hernia (CDH) outcome.
designRegistry-based cohort study using the CDH Study Group database, 1995-2013.
settingInternational multicenter database. PATIENTS: CDH patients entered into the registry. Late presenters or patients with very incomplete data were excluded. Patients were divided into three Eras (1995-2000; 2001-2006; 2007-2013).
main outcome measuresTreatment strategies and outcomes. One-way ANOVA, X2 test, and X2 test for trend were used. A Sydak-adjusted
resultsPatients: 8,603; included: 7,716; Era I: 2,146; Era II: 2,572; Era III: 2,998. From Era I to Era III, significant changes happened. Some severity indicators such as gestational age, prevalence of prenatal diagnosis, and inborn patients significantly worsened. Also, treatment strategies such as the use of prenatal steroids and inhaled nitric oxide, age at operation, prevalence of minimal access surgery, and the use of surfactant significantly changed. Finally, length of hospital stay became significantly longer and survival to discharge slightly but significantly improved, from 67.7 to 71.4% (
conclusionTreatment strategies for patients registered since 1995 in the CDH Study Group significantly changed. Survival to discharge slightly but significantly improved.
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