Evidence map›Paper›PMID 28959676›Full record

ReviewToxicology reports2017

Emerging various environmental threats to brain and overview of surveillance system with zebrafish model.

Rafael Vargas, Johny Ponce-Canchihuamán

Open access · goldAbstract readReview
In one paragraph

Review in Toxicology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Zebrafish andToxicology reports · 2021
    Article
  5. Article
  6. Review
  7. Environmental neurotoxic pollutants: review.Environmental science and pollution research international · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Rafael VargasFacultad de Salud, Universidad Manuela Beltrán, Bogotá, Colombia.
Johny Ponce-CanchihuamánCenter for Research in Environmental Health, CREEH Perú, Universidad Peruana Cayetano Heredia, Lima, Peru.
Universidad Antonio Nariño · COUniversidad Peruana Cayetano Heredia · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathologies related to neurotoxicity represent an important percentage of the diseases that determine the global burden of diseases. Neurotoxicity may be related to the increasing levels of potentially neurotoxic agents that pollute the environment, which generates concern, since agents that affect children may increase the incidence of neurodevelopmental disorders, affecting the quality of life of future citizens. Many environmental contaminants have been detected, and many of them derive from several human activities, including the mining, agriculture, manufacturing, pharmaceutical, beverage and food industries. These problems are more acute in third world countries, where environmental regulations are lax or non-existent. An additional major emerging problem is drug contamination. Periodic monitoring should be performed to identify potential neurotoxic substances using biological tests capable of identifying the risk. In this sense the fish embryo test (FET), which is performed on zebrafish embryos, is a useful, reliable and economical alternative that can be implemented in developing countries.

Indexed as

Alprazolam (PubChem CID: 2118)Arsenic (PubChem CID: 5359596)Atorvastatin (PubChem CID: 60823)Environmental contaminantsEthylene oxide (PubChem CID: 6354)Global burden diseaseLead (PubChem CID: 5352425)Mercury (PubChem CID: 23931)Methotrexate (PubChem CID: 126941)NeurotoxicityPhenythoin (PubChem CID: 1775)Toluene (PubChem CID: 1140)Trichlorethylene (PubChem CID: 6575)Zebrafish embryo test

Identifiers

PMID28959676
PMCPMC5615157
OpenAlexW2751024598

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.