ArticleToxicology reports2017
Taurine abated subacute dichlorvos toxicity.
Article in Toxicology reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 10 citations in OpenAlex.
- Synthesized novel chromogenic reagent and sensor: Detection and identification of dichlorvos.Heliyon · 2024Article
- Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models.Antioxidants (Basel, Switzerland) · 2021Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to determine the effects of taurine in rats exposed to subacute dichlorvos toxicity. Fifty rats were weighed and assigned into five groups of ten rats each. The groups received: distilled water, soya oil (1 ml/kg), taurine (50 mg/kg), dichlorvos (10 mg/kg) and the combination treatment group received taurine first and then dichlorvos 30 min later. The treatments were administered once daily by oral gavage for 4 weeks. The rats were euthanized and blood samples were collected after the termination of the study. Serum samples were analysed for malondialdehyde concentration and activities of antioxidant enzymes (superoxide dismutase and catalase). Dichlorvos increased malondialdehyde concentration and reduced the activities of superoxide dismutase and catalase. There was attenuation of malondialdehyde concentration and improvement of activities of superoxide dismutase (P = 0.0273) and catalase (P < 0.0001) in rats treated with taurine. It is postulated that taurine ameliorated dichlorvos-induced oxidative stress through the reduction of malondialdehyde concentration and the enhancement of activities of antioxidant enzymes.
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