Evidence map›Paper›PMID 28959613›Full record

ArticleToxicology reports2016

Cytotoxic and antibacterial naphthoquinones from an endophytic fungus,

Md Imdadul Huque Khan, Md Hossain Sohrab, Satyajit Roy Rony, Fakir Shahidullah Tareq, Choudhury Mahmood Hasan, Md Abdul Mazid

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 74 citations in OpenAlex.

  1. Endophytic Fungal Diversity inJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
  4. Phytotoxic Strains ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  5. Article
  6. The GenusInternational journal of molecular sciences · 2024
    Review
  7. Article
  8. Review
  9. Antibacterial Polyketides Isolated from the Marine-Derived FungusJournal of fungi (Basel, Switzerland) · 2023
    Article
  10. Journal of fungi (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Fungal Endophytes: A Potential Source of Antibacterial Compounds.Journal of fungi (Basel, Switzerland) · 2022
    Review
  14. Review
  15. NovelJournal of fungi (Basel, Switzerland) · 2021
    Article
  16. Article
  17. The GenusMolecules (Basel, Switzerland) · 2021
    Review
  18. Article
  19. Review
  20. Two new species ofBiodiversity data journal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Md Imdadul Huque KhanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Md Hossain SohrabBCSIR Laboratories Dhaka, Dr. Qudrat-I-Khuda Road, Dhanmondi, Dhaka 1205, Bangladesh.
Satyajit Roy RonyBCSIR Laboratories Dhaka, Dr. Qudrat-I-Khuda Road, Dhanmondi, Dhaka 1205, Bangladesh.
Fakir Shahidullah TareqKorea Ocean Research & Development Institute (KORDI), Ansan, Geonggi-Do, South Korea.
Choudhury Mahmood HasanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
Md Abdul MazidDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh.
University of Dhaka · BDBangladesh Council of Scientific and Industrial Research · BDKorea Institute of Ocean Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndophytes have the potential to synthesize various bioactive secondary metabolites. The aim of the study was to find new cytotoxic and antibacterial metabolites from endophytic fungus, MATERIALS AND

methodsThe endophytic fungus was grown on potato dextrose agar medium and extracted using ethyl acetate. Secondary metabolites were isolated by chromatographic separation and re-crystallization, and structures were confirmed by

resultsTwo naphthoquinones, namely anhydrofusarubin (

conclusionOur findings indicate that anhydrofusarubin (

Indexed as

Anhydrofusarubin (PubChem CID: 157509)Antibacterial activityCladosporium speciesCytoxicityEndophytic fungiFusarubinHydrogen Peroxide (PubChem CID: 784)Methyl ether of fusarubin (PubChem CID: 14050831)Triton X-100 (PubChem CID: 5590)

Identifiers

PMID28959613
PMCPMC5616083
OpenAlexW2533510557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.