Evidence map›Paper›PMID 28959608›Full record

ArticleToxicology reports2016

Genotoxic effects of synthetic amorphous silica nanoparticles in the mouse lymphoma assay.

Eşref Demir, Vincent Castranova

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Artisanal Gem Mining in Brazil: Evaluation of Oxidative Stress and Genotoxicity Biomarkers.International journal of environmental research and public health · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Genotoxicity of amorphous silica nanoparticles: Status and prospects.Nanomedicine : nanotechnology, biology, and medicine · 2019
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Eşref DemirGiresun University, Faculty of Engineering, Department of Genetics and Bioengineering, 28200-Güre, Giresun, Turkey.
Vincent CastranovaDepartment of Pharmaceutical Sciences, School of Pharmacy, RC Byrd Health Sciences Center, West Virginia University, Morgantown, WV 26506, USA.
Giresun University · TRWest Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic amorphous silica nanoparticles (SAS NPs) have been used in various industries, such as plastics, glass, paints, electronics, synthetic rubber, in pharmaceutical drug tablets, and a as food additive in many processed foods. There are few studies in the literature on NPs using gene mutation approaches in mammalian cells, which represents an important gap for genotoxic risk estimations. To fill this gap, the mouse lymphoma L5178Y/

Indexed as

In vitro mutagenicityMouse lymphoma assayMutagenic agentsSynthetic amorphous silica nanoparticlesThymidine kinase (Tk) gene

Identifiers

PMID28959608
PMCPMC5616205
OpenAlexW2535986459

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.