Transcriptomics analysis and hormonal changes of male and female neonatal rats treated chronically with a low dose of acrylamide in their drinking water.
Reyna Cristina Collí-Dulá, Marvin A Friedman, Benjamin Hansen, Nancy D Denslow
Article in Toxicology reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
4 authors at 2 institutions in 1 country.
Reyna Cristina Collí-DuláDepartment of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA.
Marvin A FriedmanKennesaw State University, Kennesaw, GA 30144, USA.
Benjamin HansenLaboratory of Pharmacology and Toxicology, D-211134, Hamburg, Germany.
Nancy D DenslowDepartment of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida, Gainesville, FL 32611, USA.
University of Florida · USKennesaw State University · US
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Acrylamide is known to produce follicular cell tumors of the thyroid in rats. RccHan Wistar rats were exposed
Indexed as
AcrylamideADA, adenosine DeaminaseADRB2, adrenergicASF1B, anti-Silencing Function 1B Histone ChaperoneBRIP1, BRCA1 Interacting Protein C-Terminal Helicase 1BUB1B, BUB1 Mitotic Checkpoint Serine/Threonine Kinase BC1QTNF3, C1q and Tumor Necrosis Factor Related Protein 3C5, complement Component 5CALCR, calcitonin receptorCARD9, caspase recruitment domain familyCCNA2, cyclin A2CCNG1, cyclin G1CD45, protein tyrosine phosphataseCD46, CD46 moleculeCDC45, cell division cycle 45CDCA2, cell division cycle associated 2CDCA5, cell division cycle associated 5CENPT, centromere protein TCFB, complement factor BCGA, glycoprotein hormonesCTLA4, cytotoxic T-lymphocyte-associated protein 4DAD1, defender against cell death 1DCTPP1, DCTP pyrophosphatase 1DNMT3A, DNA (cytosine-5-)-methyltransferase 3 alphaDUOX2, dual oxidase 2GCG, glucagonGCLC, glutamate-cysteine ligaseGOLGA3, golgin A3GSTM1, glutathione S-transferase Mu 1GSTP1, glutathione S-transferase Pi 1HPSE, heparanaseHSPA5, heat shock 70 kDa protein 5HSPB1, heat shock 27 KDa proteinHSPB2, heat shock 27 kDa protein 2HSPH1, heat shock 105 kDa/110 kDa protein 1HTATIP2, HIV-1 tat interactive protein 2ID1, inhibitor of DNA binding 1IGF2, Insulin-like growth factor 2 (somatomedin A)IL1B, interleukin 1INHBA, inhibinIYD, iodotyrosine deiodinaseKIF20B, kinesin family member 20BKIF22, kinesin family Member 22KLK1, kallikrein 1LAMA2, laminin, alpha 2MCM8, minichromosome maintenance complex component 8MIF, macrophage migration inhibitory factorMIS18A, MIS18 kinetochore protein ANDC80, NDC80 kinetochore complex componentNPPC, natriuretic peptide precursor CNPY, neuropeptideNUBP1, nucleotide binding protein 1ORC1, origin recognition complexPDE3A, phosphodiesterase 3APINK1, PTEN induced putative kinase 1PLCD1, phospholipase CPLK1, polo-like kinase 1POMC, proopiomelanocortinPRKAA2, protein kinasePRL, prolactinPRODH, proline dehydrogenasePTGIS, prostaglandin I2 (prostacyclin) synthasePTGS1, prostaglandin-endoperoxide synthase 1RAB5A, RAB5ARAN, ras-related nuclear proteinRccHan WistarRRM2, ribonucleotide reductase M2SCL5A5, solute carrier family 5 (sodium iodide symporter)SELP, selectin P (granule membrane protein 140 kDaSPAG8, sperm associated antigen 8TACC3, transformingTBCB, tubulin folding cofactor BTFRC, transferrin receptorThyroidTOP2A, topoisomerase (DNA) II alphaTPO, thyroid peroxidaseTranscriptomicsTSHR, thyroid stimulating hormone receptorTSN, translinVWF, Von Willebrand Factor
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Transcriptomics analysis and hormonal changes of male and female neonatal rats treated chronically with a low dose of acrylamide in their drinking water. · full record | OpenQuestion