ArticleThe World Allergy Organization journal2017
Debates in allergy medicine: Molecular allergy diagnosis with ISAC will replace screenings by skin prick test in the future.
Article in The World Allergy Organization journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Innovative diagnostic techniques and their clinical implications in food allergy: current clinical practice and future perspectives.Frontiers in allergy · 2026Review
- Prick test accuracy for Der p components in pediatric rhinitis.European journal of pediatrics · 2025Article
- Component-Resolved and Multiplex-Specific IgE Diagnostics: Utility in Anaphylaxis and Beyond.Children (Basel, Switzerland) · 2025Review
- Skin prick tests are not useful for the qualification for venom immunotherapy in children.The World Allergy Organization journal · 2023Article
- The use of microarray and other multiplex technologies in the diagnosis of allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021Review
- Symptom patterns and comparison of diagnostic methods in ragweed pollen allergy.Experimental and therapeutic medicine · 2021Article
- VALIDA project: Validation of allergyAdvances in laboratory medicine · 2020Review
- Skin prick reactivity among asthmatics in East Africa.The World Allergy Organization journal · 2020Article
- A WAO - ARIA - GAThe World Allergy Organization journal · 2020Article
- IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper.The World Allergy Organization journal · 2020Article
- Food-dependent exercise-induced reactions: lessons from a 15-year retrospective study.Irish journal of medical science · 2019Article
- Molecular Allergy Diagnostics as an Adjunct to Conventional Diagnostics in a Secondary Pediatric Referral Center.Recent patents on inflammation & allergy drug discovery · 2019Observational
- Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules.World journal of methodology · 2018Article
- Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer.Allergy · 2018Article
- The potential of component-resolved diagnosis in laboratory diagnostics of allergy.Biochemia medica · 2018Review
- Allergy diagnosis from symptoms to molecules, or from molecules to symptoms: a comparative clinical study.The World Allergy Organization journal · 2018Article
- Prevalence of food allergens sensitization and food allergies in a group of allergic Honduran children.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018Article
- Article
- Analysis of a Large Standardized Food Challenge Data Set to Determine Predictors of Positive Outcome Across Multiple Allergens.Frontiers in immunology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In today's clinical practice patients' skin is used as screening organ for diagnosing type 1 allergy. According to European guidelines skin prick testing with a panel of 18 allergen extracts is recommended, in the US between 10 to 50 allergens are used. The specificity and sensitivity of skin testing is individually highly variable depending on age, body mass, and skin barrier status. In atopic inflammation skin testing gives more false positive results. Smaller skin area and strain limits prick testing in small children. Although the risk for systemic reactions in skin prick testing is very small, emergency medications must be available. Considering the fact that IgE is the only reliable biomarker for type I allergy, upfront IgE screening with ISAC, followed by fewer skin tests to approve positive sensitizations, is proposed. It is time to arrive in the age of molecular allergy diagnosis in daily patient care.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.