ArticleFrontiers in microbiology2017
Microbiome-Metabolome Responses to a High-Grain Diet Associated with the Hind-Gut Health of Goats.
Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Subacute ruminal acidosis in high-producing dairy cows: an integrated diet-microbiota-epithelium-host framework for diagnosis and nutritional management.Journal of animal science and biotechnology · 2026Review
- Plant extracts to enhancing intestinal barrier function in fattening lambs: review.Animal bioscience · 2026Article
- Effects of Composite Antimicrobial Peptides on Colonic Microbiota and Barrier Integrity in Holstein Steers.Probiotics and antimicrobial proteins · 2026Article
- Segment-specific intestinal bacterial community structure is associated with short-chain fatty acid profiles and mucosal morphology in two high-altitude sheep breeds.Frontiers in microbiology · 2026Article
- Effects of Postpartal Relative Body Weight Change on Production Performance, Serum Biomarkers, and Fecal Microbiota in Multiparous Holstein Cows.Animals : an open access journal from MDPI · 2025Article
- Multi-Omics Analysis Reveals the Negative Effects of High-Concentrate Diets on the Colonic Epithelium of Dumont Lambs.Animals : an open access journal from MDPI · 2025Article
- The role ofFrontiers in veterinary science · 2025Article
- Multi-omics reveal mechanisms of high enteral starch diet mediated colonic dysbiosis via microbiome-host interactions in young ruminant.Microbiome · 2024Article
- Effect of a High-Starch or a High-Fat Diet on the Milk Performance, Apparent Nutrient Digestibility, Hindgut Fermentation Parameters and Microbiota of Lactating Cows.Animals : an open access journal from MDPI · 2023Article
- Exploring the digesta- and mucosa-associated microbial community dynamics in the rumen and hindgut of goats from birth to adult.Frontiers in microbiology · 2023Article
- Dietary Nutritional Level Affects Intestinal Microbiota and Health of Goats.Microorganisms · 2022Article
- Ameliorative effects of supranutritional selenium on TLR-4-NF-kB-TNF-α-mediated hepatic oxidative injury and inflammation in goats fed high concentrate diet.Food science & nutrition · 2022Article
- Effect of Chinese Herbs on Serum Biochemical Parameters, Immunity Indices, Antioxidant Capacity and Metabolomics in Early Weaned Yak Calves.Animals : an open access journal from MDPI · 2022Article
- Characterization of microbial intolerances and ruminal dysbiosis towards different dietary carbohydrate sources using an in vitro model.Journal of applied microbiology · 2022Article
- Differential Responses of Digesta- and Mucosa-Associated Jejunal Microbiota of Hu Sheep to Pelleted and Non-Pelleted High-Grain Diets.Animals : an open access journal from MDPI · 2022Article
- Article
- Metabolomic Investigation of Ultraviolet Ray-Inactivated White Spot Syndrome Virus-Induced Trained Immunity inFrontiers in immunology · 2022Article
- The gut microbiome as an indicator of habitat disturbance in a Critically Endangered lemur.BMC ecology and evolution · 2021Article
- Sulforaphane protects intestinal epithelial cells against lipopolysaccharide-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway.Bioengineered · 2021Article
- Rumen-protected glucose supplementation in transition dairy cows shifts fermentation patterns and enhances mucosal immunity.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on the effect of a high-concentrate (HC) diet on the hindgut microbiota and metabolome of ruminants are rarely reported. We used 454 pyrosequencing of 16S rDNA genes and gas chromatography-mass spectrometry to evaluate the effects of long-term feeding (HL) or short-term (HS) feeding of an HC diet on changes in bacterial microbiota and their metabolites in the hindgut, with Guanzhong goat as a ruminant model. Results indicated that an HC diet decreased bacterial diversity and induced metabolic disorder in the hindgut. The levels of lactate, endotoxin (lipopolysaccharide, LPS), and volatile fatty acid concentrations were higher in the intestinal digesta of the HC goats than in those of the LC goats (
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