Evidence map›Paper›PMID 28959213›Full record

ArticleFrontiers in physiology2017

Postnatal Craniofacial Skeletal Development of Female C57BL/6NCrl Mice.

Xiaoxi Wei, Neil Thomas, Nan E Hatch, Min Hu, Fei Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 59 citations in OpenAlex.

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  10. Achondroplasia: aligning mouse model with human clinical studies shows crucial importance of immediate postnatal start of the therapy.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
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  11. Intact-skull cranial windows for widefield optical imaging in juvenile mice: complications and consequences.Journal of the Optical Society of America. A, Optics, image science, and vision · 2024
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  16. Infigratinib, a selective FGFR1-3 tyrosine kinase inhibitor, alters dentoalveolar development at high doses.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xiaoxi WeiDepartment of Orthodontics, Jilin University School and Hospital of StomatologyChangchun, China.
Neil ThomasDepartment of Biologic and Materials Sciences and Division of Prosthodontics, University of Michigan School of DentistryAnn Arbor, MI, United States.
Nan E HatchDepartment of Orthodontics and Pediatric Dentistry, University of Michigan School of DentistryAnn Arbor, MI, United States.
Min HuDepartment of Orthodontics, Jilin University School and Hospital of StomatologyChangchun, China.
Fei LiuDepartment of Biologic and Materials Sciences and Division of Prosthodontics, University of Michigan School of DentistryAnn Arbor, MI, United States.
University of Michigan–Ann Arbor · USJilin University · CN

Funding

Structure, Composition, & Histology Core - Core BP30AR069620 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KARL J JEPSEN · 2016 to 2026
$8.4M
Molecular Mechanisms of CraniosynostosisR01DE025827 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HATCH, NAN E · 2016 to 2020
$2.0M
The Mechanisms of Bone Mass Regulation by FIP200R01AR062030 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, FEI · 2012 to 2016
$1.7M
NIAMS NIH HHS P30 AR069620NIAMS NIH HHS R01 AR062030NIDCR NIH HHS R01 DE025827
6 · The paper itself

Abstract

The craniofacial skeleton is a complex and unique structure. The perturbation of its development can lead to craniofacial dysmorphology and associated morbidities. Our ability to prevent or mitigate craniofacial skeletal anomalies is at least partly dependent on our understanding of the unique physiological development of the craniofacial skeleton. Mouse models are critical tools for the study of craniofacial developmental abnormalities. However, there is a lack of detailed normative data of mouse craniofacial skeletal development in the literature. In this report, we employed high-resolution micro-computed tomography (μCT) in combination with morphometric measurements to analyze the postnatal craniofacial skeletal development from day 7 (P7) through day 390 (P390) of female C57BL/6NCrl mice, a widely used mouse strain. Our data demonstrates a unique craniofacial skeletal development pattern in female C57BL/6NCrl mice, and differentiates the early vs. late craniofacial growth patterns. Additionally, our data documents the complex and differential changes in bone parameters (thickness, bone volume, bone volume/tissue volume, bone mineral density, and tissue mineral density) of various craniofacial bones with different embryonic origins and ossification mechanisms during postnatal growth, which underscores the complexity of craniofacial bone development and provides a reference standard for future quantitative analysis of craniofacial bones.

Indexed as

boneC57BL/6NCrlcranial basecraniofacialmousepostnatalsynchondrosesμCT

Identifiers

PMID28959213
PMCPMC5603710
OpenAlexW2755675592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.