Evidence map›Paper›PMID 28959163›Full record

ArticleRadiology and oncology2017

Quantitative Aspects of Diffusion-weighted Magnetic Resonance Imaging in Rectal Cancer Response to Neoadjuvant Therapy.

Thiago Bassaneze, José Eduardo Gonçalves, Juliano Ferreira Faria, Rogério Tadeu Palma, Jaques Waisberg

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology and oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Integrated slice-specific dynamic shimming diffusion weighted imaging (DWI) for rectal Cancer detection and characterization.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Article
  6. Article
  7. Observational
  8. Review
  9. Review
  10. Diffusion-weighted imaging of rectal cancer on repeatability and cancer characterization: an effect of b-value distribution study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thiago BassanezeDepartment of Gastrointestinal Surgery, State Public Servant Hospital of São Paulo, São Paulo, Brazil.
José Eduardo GonçalvesDepartment of Gastrointestinal Surgery, State Public Servant Hospital of São Paulo, São Paulo, Brazil.
Juliano Ferreira FariaDepartment of Diagnostic Imaging, Federal University of São Paulo, São Paulo, Brazil.
Rogério Tadeu PalmaDepartment of Gastrointestinal Surgery, State Public Servant Hospital of São Paulo, São Paulo, Brazil.
Jaques WaisbergDepartment of Gastrointestinal Surgery, State Public Servant Hospital of São Paulo, São Paulo, Brazil.
Faculdade de Medicina do ABC · BRHospital do Servidor Público Municipal · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study was to evaluate the added value of the apparent diffusion coefficient (ADC) of diffusion-weighted magnetic resonance imaging (DW-MRI) in patients with rectal cancer who received neoadjuvant chemoradiotherapy (CRT). The use of DW-MRI for response evaluation in rectal cancer still remains a widely investigated issue, as the accurate detection of pathologic complete response (pCR) is critical in making therapeutic decisions. PATIENTS AND

methodsThirty-three patients with locally advanced rectal cancer were evaluated retrospectively by MRI in addition to diffusion-weighted images (DWI) and its ADC pre- and post-neoadjuvant CRT. These patients subsequently underwent curative-intent surgery. Tumor staging by MRI and ADC value were compared with histopathological findings of the surgical specimen.

resultsMRI in addition to DWI had a sensitivity of 96.1%, specificity of 71.4%, positive predictive value of 92.5%, and negative predictive value of 83.3% in the detection of pCR. The pre-CRT ADC alone could not reliably predict the pCR group. Post-CRT ADC cutoff value of 1.49 x 10

conclusionsThe use of post-CRT ADC increased the diagnostic performance of MRI in addition to DWI in predicting the final pathologic staging of rectal carcinoma.

Indexed as

diffusion MRIneoadjuvant therapyrectal cancer

Identifiers

PMID28959163
PMCPMC5611991
OpenAlexW2730120934

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.