Evidence map›Paper›PMID 28959158›Full record

Trial reportJournal of the International Society of Sports Nutrition2017

Effects of a pre-workout supplement on hyperemia following leg extension resistance exercise to failure with different resistance loads.

Jeffrey S Martin, Petey W Mumford, Cody T Haun, Micheal J Luera, Tyler W D Muddle, Ryan J Colquhoun, Mary P Feeney, Cameron S Mackey, Paul A Roberson, Kaelin C Young and 4 more

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Effects of Theacrine as a Pre-Workout Supplement.International journal of environmental research and public health · 2022
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  3. Trial
  4. Trial
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Jeffrey S MartinSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Petey W MumfordSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Cody T HaunSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Micheal J LueraSchool of Kinesiology, Applied Health and Recreation, Oklahoma State University, Stillwater, OK 74078 USA.
Tyler W D MuddleSchool of Kinesiology, Applied Health and Recreation, Oklahoma State University, Stillwater, OK 74078 USA.
Ryan J ColquhounSchool of Kinesiology, Applied Health and Recreation, Oklahoma State University, Stillwater, OK 74078 USA.
Mary P FeeneySchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Cameron S MackeySchool of Kinesiology, Applied Health and Recreation, Oklahoma State University, Stillwater, OK 74078 USA.
Paul A RobersonSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Kaelin C YoungSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
David D PascoeSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Jason M DeFreitasSchool of Kinesiology, Applied Health and Recreation, Oklahoma State University, Stillwater, OK 74078 USA.
Nathaniel D M JenkinsSchool of Kinesiology, Applied Health and Recreation, Oklahoma State University, Stillwater, OK 74078 USA.
Michael D RobertsSchool of Kinesiology, Auburn University, Auburn, AL 36849 USA.
Auburn University · USOklahoma State University · USEdward Via College of Osteopathic Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe sought to determine if a pre-workout supplement (PWS), containing multiple ingredients thought to enhance blood flow, increases hyperemia associated with resistance training compared to placebo (PBO). Given the potential interaction with training loads/time-under-tension, we evaluated the hyperemic response at two different loads to failure.

methodsThirty males participated in this double-blinded study. At visit 1, participants were randomly assigned to consume PWS (Reckless™) or PBO (maltodextrin and glycine) and performed four sets of leg extensions to failure at 30% or 80% of their 1-RM 45-min thereafter. 1-wk. later (visit 2), participants consumed the same supplement as before, but exercised at the alternate load. Heart rate (HR), blood pressure (BP), femoral artery blood flow, and plasma nitrate/nitrite (NOx) were assessed at baseline (BL), 45-min post-PWS/PBO consumption (PRE), and 5-min following the last set of leg extensions (POST).

resultsWith the 30% training load compared to 80%, significantly more repetitions were performed (

conclusionsCompared to PBO, the PWS consumed herein augmented hyperemia following multiple sets to failure at 80% of 1-RM, but not 30%. This specificity may be a product of interaction with local perturbations (e.g., reduced tissue oxygenation levels [minimum O

Indexed as

Dietary SupplementsResistance TrainingSports Nutritional Physiological PhenomenaAdultDouble-Blind MethodEnergy MetabolismFemoral ArteryHealthy VolunteersHeart RateHumansHyperemiaLegMaleMuscle, SkeletalMuscle StrengthOxygen ConsumptionBlood flowNitric oxide, Volume loadOxygenationReactive hyperemiaResistance exerciseSports supplements

Identifiers

PMID28959158
PMCPMC5615454
OpenAlexW2758508611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.