Evidence map›Paper›PMID 28959099›Full record

ArticleActa Cardiologica Sinica2017

Systemic Inflammatory Response Syndrome is an Independent Predictor of One-Year Mortality in Patients with Acute Myocardial Infarction.

Wei-Chieh Huang, Ruey-Hsing Chou, Chun-Chin Chang, Chien-Yi Hsu, Yu-Chen Ku, Hsiu-Fen Huang, Yi-Chieh Chen, Po-Hsun Huang

Abstract read
In one paragraph

Article in Acta Cardiologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Wei-Chieh HuangDivision of Cardiology, Department of Medicine.
Ruey-Hsing ChouDivision of Cardiology, Department of Medicine.
Chun-Chin ChangCardiovascular Research Center.
Chien-Yi HsuCardiovascular Research Center.
Yu-Chen KuNursing Department, Taipei Veterans General Hospital, Taipei.
Hsiu-Fen HuangNursing Department, Taipei Veterans General Hospital, Taipei.
Yi-Chieh ChenNursing Department, Taipei Veterans General Hospital, Taipei.
Po-Hsun HuangDivision of Cardiology, Department of Medicine.
Taipei Veterans General Hospital · TWInstitute of Clinical Research · USCardiovascular Research Center · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConvincing evidence suggests that inflammatory biomarkers are associated with an increased risk among patients with acute myocardial infarction (AMI). However, the impact of systemic inflammatory response (SIRS) on one-year clinical outcomes remains uncertain. Herein we investigated the impact of SIRS on one-year mortality and major adverse cardiovascular events (MACE) in patients with AMI.

methodsWe conducted a retrospective study that enrolled patients admitted due to AMI and who received coronary artery intervention from January 2012 to June 2014. SIRS was defined according to standard criteria as having two or more of the following: (1) body temperature < 36 or > 38 °C, (2) heart rate > 90 beats per minute, (3) respiratory rate > 20, or (4) white blood cell count < 4000/mm

resultsA total of 330 AMI patients were enrolled in the study, and 121 study subjects (36.6%) met the SIRS criteria. AMI patients with SIRS on admission had significantly increased one-year all-cause mortality (control vs. SIRS: 21.1% vs. 33.1%, p = 0.026) and one-year MACE (35.9% vs. 53.7%, p = 0.022). Patients with SIRS had a higher incidence of one-year non-fatal myocardial infarction, but not non-fatal stroke. After multivariable adjustment, SIRS [hazard ratio (HR) = 1.773, 95% confidence interval (CI) = 1.097-2.886, p = 0.019] and age (HR = 1.038, 95% CI = 1.018-1.058, p < 0.001) were associated with enhanced risk of one-year mortality.

conclusionsThis study revealed that AMI patients with SIRS on initial admission were associated with increased risk of one-year all-cause mortality.

Indexed as

Myocardial infarctionSystemic inflammatory response syndrome

Identifiers

PMID28959099
PMCPMC5611343
OpenAlexW2914805090

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.