Evidence map›Paper›PMID 28959033›Full record

ArticleScientific reports2017

Temperature-dependent sex-reversal by a transformer-2 gene-edited mutation in the spotted wing drosophila, Drosophila suzukii.

Jianwei Li, Alfred M Handler

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Review
  9. The shibireInsect science · 2026
    Article
  10. Article
  11. Decoding and engineering temperature-sensitive lethality inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. The Roles ofInsects · 2023
    Article
  15. Article
  16. Article
  17. Highly Efficient Temperature Inducible CRISPR-Cas9 Gene Targeting inInternational journal of molecular sciences · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jianwei LiUSDA/ARS, Center for Medical, Agricultural and Veterinary Entomology, 1700 SW 23rd Drive, Gainesville, FL, 32608, USA. jianwei.li@ars.usda.gov.ORCID 0000-0002-0262-3901
Alfred M HandlerUSDA/ARS, Center for Medical, Agricultural and Veterinary Entomology, 1700 SW 23rd Drive, Gainesville, FL, 32608, USA.
Center for Medical, Agricultural and Veterinary Entomology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Female to male sex reversal was achieved in an emerging agricultural insect pest, Drosophila suzukii, by creating a temperature-sensitive point mutation in the sex-determination gene, transformer-2 (tra-2), using CRISPR/Cas9 (clustered regularly interspaced palindromic repeats/CRISPR-associated) homology-directed repair gene-editing. Ds-tra-2

Indexed as

MutationTemperatureAnimalsCRISPR-Cas SystemsDrosophilaDrosophila ProteinsGene EditingMalePhenotypeRibonucleoproteinsVitellogeninsDrosophila ProteinsRibonucleoproteinstra2 protein, DrosophilaVitellogeninsYP1 protein, Drosophila

Identifiers

PMID28959033
PMCPMC5620132
OpenAlexW2760249327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.