Evidence map›Paper›PMID 28958894›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2018

Donor Experiences of Second Marrow or Peripheral Blood Stem Cell Collection Mirror the First, but CD34

David F Stroncek, Bronwen E Shaw, Brent R Logan, Deidre M Kiefer, Bipin N Savani, Paolo Anderlini, Christopher N Bredeson, Peiman Hematti, Siddhartha Ganguly, Miguel Angel Diaz and 23 more

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In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 20 institutions in 6 countries.

David F StroncekDepartment of Transfusion Medicine, Cell Processing Section, Clinical Center, National Institutes of Health, Bethesda, Maryland.
Bronwen E ShawCenter for International Blood and Bone Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: beshaw@mcw.edu.
Brent R LoganCenter for International Blood and Bone Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin.
Deidre M KieferCenter for International Blood and Bone Marrow Transplant Research, National Marrow Donor Program, Minneapolis, Minnesota.
Bipin N SavaniHematology & Stem Cell Transplantation, Vanderbilt University Medical Center, Nashville, Tennessee.
Paolo AnderliniStem Cell Transplantation and Cellular Therapy, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.
Christopher N BredesonThe Ottawa Hospital Blood & Marrow Transplant Program, University of Ottawa, Ottawa, Ontario, Canada.
Peiman HemattiDepartment of Medicine, University of Wisconsin, Madison, Wisconsin.
Siddhartha GangulyHematologic Malignancies and Cellular Therapies, University of Kansas Medical Center, Westwood, Kansas.
Miguel Angel DiazUnidad de Trasplante Hematopoyetico, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Hisham Abdel-AzimDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California.
Ibrahim AhmedChildren's Mercy Hospital-UMKC, Kansas City, Missouri.
Dipnarine MaharajSouth Florida Bone Marrow Transplant/Stem Cell Transplant Institute, Bethesda Health City, Boynton Beach, Florida.
Matthew SeftelMedical Oncology and Haematology, CancerCare Manitoba, Winnipeg, Ontario, Canada.
Amer BeitinjanehStem Cell Transplantation and Cell Therapy Program, Miller School of Medicine, University of Miami, Miami, Florida.
Sachiko SeoVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Jean A YaredDepartment of Medicine, Greenbaum Cancer Center, University of Maryland, Baltimore, Maryland.
Joerg HalterDepartment of Haematology, University Hospital Basel, Basel, Switzerland.
Paul V O'DonnellBlood and Marrow Transplant Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Gregory A HaleCancer and Blood Disorders Institute, All Children's Hospital, St. Petersburg, Florida.
Zachariah DeFilippBlood and Marrow Transplant Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Hillard LazarusDepartment of Medicine, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio.
Jane L LiesveldHematology-Oncology Unit, Department of Medicine, Strong Memorial Hospital, University of Rochester Medical Center, Rochester, New York.
Zheng ZhouUniversity of Massachusetts, Marlboro, Massachusetts.
Pashna MunshiGeorgetown University Hospital, Washington, District of Columbia.
Richard F OlssonKarolinska Institutet, Division of Therapeutic Immunology, Stockholm, Sweden.
Kimberly Anne KasowDivision of Hematology-Oncology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Jeffrey SzerDepartment of Hematology and Bone Marrow Transplantation, Royal Melbourne Hospital City Campus, Victoria, Australia.
Galen E SwitzerDepartment of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Pintip ChitphakdithaiCenter for International Blood and Bone Marrow Transplant Research, National Marrow Donor Program, Minneapolis, Minnesota.
Nirali ShahPediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Dennis L ConferCenter for International Blood and Bone Marrow Transplant Research, National Marrow Donor Program, Minneapolis, Minnesota.
Michael A PulsipherDepartment of Pediatrics, Children's Hospital Los Angeles, Los Angeles, California.
National Marrow Donor Program · USChildren's Hospital of Los Angeles · USHarvard University · USMedical College of Wisconsin · USCancerCare Manitoba · CACenter for Cancer and Blood Disorders · USChildren's Mercy Hospital · USFred Hutch Cancer Center · USGeorgetown University · USHospital Infantil Universitario Niño Jesús · ESKarolinska Institutet · SEMarlboro College · USNational Cancer Institute · USNational Institutes of Health Clinical Center · USOttawa Hospital · CAThe Royal Melbourne Hospital · AUThe University of Texas MD Anderson Cancer Center · USUniversity Hospital of Basel · CHUniversity Hospitals Case Medical Center · USUniversity of Kansas Medical Center · US

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Easy-to-read Informed Consent for HCT Clinical TrialsU10HL069294 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HOROWITZ, MARY MARESCA · 2011 to 2016
$43.8M
NCI NIH HHS U24 CA076518NHLBI NIH HHS U10 HL069294
6 · The paper itself

Abstract

Little is known about the experiences of individuals donating peripheral blood stem cells (PBSCs) or marrow for a second time. To study this, unrelated donors making a second donation through the National Marrow Donor Program between 2004 and 2013 were evaluated. Experiences of second-time donors giving marrow (n = 118: first donation was PBSC in 76 and marrow in 42) were compared with those making only 1 marrow donation (n = 5829). Experiences of second-time donors giving PBSCs (n = 602) (first donation was PBSCs in 362; marrow in 240) were compared to first-time PBSC donors (n = 16,095). For donors giving a second PBSC or marrow donation there were no significant differences in maximum skeletal pain, maximum symptoms measured by an established modified toxicity criteria, and recovery time compared with those who donated only once. Notably, the yield of marrow nucleated cells and PBSC CD34

Indexed as

Bone MarrowPeripheral Blood Stem CellsUnrelated DonorsAdolescentAdultAntigens, CD34Body WeightHumansMiddle AgedPainReoperationSex FactorsTransplantation, HomologousYoung AdultAntigens, CD34Bone marrowHematopoietic cell transplantationPeripheral blood stem cellsUnrelated donor

Identifiers

PMID28958894
PMCPMC5743544
OpenAlexW2759594404

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.