Evidence map›Paper›PMID 28958744›Full record

Trial reportThe journal of allergy and clinical immunology. In practice

Very Poorly Controlled Asthma in Urban Minority Children: Lessons Learned.

Arlene M Butz, Melissa Bellin, Mona Tsoukleris, Shawna S Mudd, Joan Kub, Jean Ogborn, Tricia Morphew, Cassia Lewis-Land, Mary Elizabeth Bollinger

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Pattern of medication use in children with very poorly controlled asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Trial
  2. Article
  3. Association between second hand smoke (SHS) exposure and caregiver stress in children with poorly controlled asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Arlene M ButzDepartment of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Md. Electronic address: abutz@jhmi.edu.
Melissa BellinSchool of Social Work, The University of Maryland, Baltimore, Md.
Mona TsouklerisThe School of Pharmacy, The University of Maryland, Baltimore, Md.
Shawna S MuddThe Johns Hopkins University School of Nursing, Baltimore, Md.
Joan KubThe Johns Hopkins University School of Nursing, Baltimore, Md.
Jean OgbornDepartment of Pediatric Emergency Medicine, The Johns Hopkins University School of Medicine, Baltimore, Md.
Tricia MorphewMorphew Consulting LLC, Bothell, Wash.
Cassia Lewis-LandDepartment of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Md.
Mary Elizabeth BollingerDepartment of Pediatrics, School of Medicine, The University of Maryland, Baltimore, Md.
Johns Hopkins Medicine · USUniversity of Maryland, Baltimore · USJohns Hopkins University · US

Funding

Institute for Clinical and Translational ResearchUL1TR000424 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2012 to 2012
$6.0M
Asthma Express: Bridging Emergency to Primary Care in Underserved ChildrenR01NR013486 · NINR · JOHNS HOPKINS UNIVERSITY · PI BUTZ, ARLENE MANNS · 2013 to 2017
$2.3M
NCATS NIH HHS UL1 TR000424NINR NIH HHS R01 NR013486
6 · The paper itself

Abstract

backgroundVery poorly controlled (VPC) asthma in children is associated with ongoing acute exacerbations but factors associated with VPC are understudied.

objectiveTo examine the risk factors associated with VPC asthma in urban minority children.

methodsThis descriptive study examined asthma control levels (well-controlled [WC], not well-controlled [NWC], and VPC) at baseline and 6 months in children participating in an ongoing randomized controlled trial of an emergency department/home environmental control intervention. Data collection occurred during the index emergency department visit and included allergen-specific IgE and salivary cotinine testing and caregiver interview of sociodemographic and child health characteristics. Follow-up data were collected at 6 months. Unadjusted analyses examined the association of sociodemographic and health characteristics by level of asthma control. Multivariate analysis tested significant factors associated with VPC asthma at 6 months.

resultsAt baseline most children were categorized with VPC asthma (WC, 0%; NWC, 47%; VPC, 53%) and rates of VPC minimally improved at 6 months (WC, 13%; NWC, 41%; VPC, 46%). Risk for VPC asthma was twice as likely in children with allergic rhinitis (odds ratio [OR], 2.42), having 2 or more primary care provider asthma visits within the past 3 months (OR, 2.77), or caregiver worry about medication side effects (OR, 2.13) and 3 to 4 times more likely when asthma control was assessed during the fall or spring season (OR: fall, 3.32; spring, 4.14).

conclusionsImproving asthma control in low-income, high-risk children with VPC asthma requires treatment of comorbidities, attention to caregiver medication beliefs, and adept use of stepwise therapy.

Indexed as

Anti-Asthmatic AgentsAsthmaCaregiversChildChild, PreschoolCotinineEmergency Medical ServicesEnvironmentFemaleHealth Knowledge, Attitudes, PracticeHumansImmunoglobulin EMaleMinority GroupsPovertyRhinitis, AllergicAnti-Asthmatic AgentsCotinineImmunoglobulin ETobacco Smoke PollutionAsthma controlChildrenStepwise therapyVery poorly controlled asthma

Identifiers

PMID28958744
PMCPMC5862725
OpenAlexW2758014218

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.