Evidence map›Paper›PMID 28958577›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2017

Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells.

Lynsey M Whilding, Ana C Parente-Pereira, Tomasz Zabinski, David M Davies, Roseanna M G Petrovic, Y Vincent Kao, Shobhit A Saxena, Alex Romain, Jose A Costa-Guerra, Shelia Violette and 5 more

Open access · hybridAbstract readPublished Erratum
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. How Can We Engineer CAR T Cells to Overcome Resistance?Biologics : targets & therapy · 2021
    Review
  11. Review
  12. Article
  13. Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells.Mammalian genome : official journal of the International Mammalian Genome Society · 2018
    Review
  14. Article
  15. Genetically engineered T cells for cancer immunotherapy.Signal transduction and targeted therapy
    Review
  16. New Therapeutic Options for Advanced Hepatocellular Carcinoma.Cancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 3 countries.

Lynsey M Whilding
Ana C Parente-Pereira
Tomasz Zabinski
David M Davies
Roseanna M G Petrovic
Y Vincent Kao
Shobhit A Saxena
Alex Romain
Jose A Costa-Guerra
Shelia Violette
Hiroaki Itamochi
Sadaf Ghaem-Maghami
Sabari Vallath
John F Marshall
John Maher
Queen Mary University of London · GBBiogen (United States) · USImperial College London · GBIwate Medical University · JP

Funding

Cancer Research UK 16880Cancer Research UK 21624Medical Research Council G0800825Medical Research Council MC_PC_14105Worldwide Cancer Research 13-1017
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID28958577
PMCPMC5883575
OpenAlexW2567725515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.