Evidence map›Paper›PMID 28958414›Full record

ArticleEpidemics2018

The RAPIDD ebola forecasting challenge: Synthesis and lessons learnt.

Cécile Viboud, Kaiyuan Sun, Robert Gaffey, Marco Ajelli, Laura Fumanelli, Stefano Merler, Qian Zhang, Gerardo Chowell, Lone Simonsen, Alessandro Vespignani and 1 more

Abstract read
In one paragraph

Article in Epidemics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  7. Local Influenza Forecasts Outperform State-Level Forecasts in the United States.medRxiv : the preprint server for health sciences · 2026
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  12. Leveraging probabilistic forecasts for dengue preparedness and control: The 2024 Dengue Forecasting Sprint in Brazil.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  14. Coordinating collaborative infectious disease modeling projects with the hubverse.medRxiv : the preprint server for health sciences · 2025
    Article
  15. Review
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  17. What can we learn from 100,000 freshwater forecasts? A synthesis from the NEON Ecological Forecasting Challenge.Ecological applications : a publication of the Ecological Society of America · 2025
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  20. Mathematical modelling for pandemic preparedness in Canada: Learning from COVID-19.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cécile ViboudDivision of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA. Electronic address: viboudc@mail.nih.gov.
Kaiyuan SunLaboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA, USA.
Robert GaffeyDivision of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
Marco AjelliBruno Kessler Foundation, Trento, Italy.
Laura FumanelliBruno Kessler Foundation, Trento, Italy.
Stefano MerlerBruno Kessler Foundation, Trento, Italy.
Qian ZhangLaboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA, USA.
Gerardo ChowellDivision of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA; School of Public Health, Georgia State University, Atlanta, GA, USA.
Lone SimonsenDivision of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, MD, USA; Department of Global Health, George Washington University, Washington DC, USA.
Alessandro VespignaniLaboratory for the Modeling of Biological and Socio-technical Systems, Northeastern University, Boston, MA, USA; Institute for Quantitative Social Sciences at Harvard University, Cambridge, MA, USA; Institute for Scientific Interchange Foundation, Turin, Italy.
RAPIDD Ebola Forecasting Challenge group

Funding

Understanding Transmission with Integrated Genetic and Epidemiologic InferenceU54GM111274 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI VESPIGNANI, ALESSANDRO · 2014 to 2018
$12.5M
Intramural NIH HHS Z99 TW999999NIGMS NIH HHS U54 GM111274
6 · The paper itself

Abstract

Infectious disease forecasting is gaining traction in the public health community; however, limited systematic comparisons of model performance exist. Here we present the results of a synthetic forecasting challenge inspired by the West African Ebola crisis in 2014-2015 and involving 16 international academic teams and US government agencies, and compare the predictive performance of 8 independent modeling approaches. Challenge participants were invited to predict 140 epidemiological targets across 5 different time points of 4 synthetic Ebola outbreaks, each involving different levels of interventions and "fog of war" in outbreak data made available for predictions. Prediction targets included 1-4 week-ahead case incidences, outbreak size, peak timing, and several natural history parameters. With respect to weekly case incidence targets, ensemble predictions based on a Bayesian average of the 8 participating models outperformed any individual model and did substantially better than a null auto-regressive model. There was no relationship between model complexity and prediction accuracy; however, the top performing models for short-term weekly incidence were reactive models with few parameters, fitted to a short and recent part of the outbreak. Individual model outputs and ensemble predictions improved with data accuracy and availability; by the second time point, just before the peak of the epidemic, estimates of final size were within 20% of the target. The 4th challenge scenario - mirroring an uncontrolled Ebola outbreak with substantial data reporting noise - was poorly predicted by all modeling teams. Overall, this synthetic forecasting challenge provided a deep understanding of model performance under controlled data and epidemiological conditions. We recommend such "peace time" forecasting challenges as key elements to improve coordination and inspire collaboration between modeling groups ahead of the next pandemic threat, and to assess model forecasting accuracy for a variety of known and hypothetical pathogens.

Indexed as

Models, StatisticalBayes TheoremEpidemicsForecastingHemorrhagic Fever, EbolaHumansLiberiaReproducibility of ResultsData accuracyEbola epidemicForecasting challengeMathematical modelingModel comparisonPrediction horizonPrediction performanceSynthetic data

Identifiers

PMID28958414
PMCPMC5927600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.