Evidence map›Paper›PMID 28958167›Full record

ArticleThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2019

Age at menarche and the risk of operative delivery.

Hsu Phern Chong, J Frederik Frøen, Sylvia Richardson, Benoit Liquet, D Stephen Charnock-Jones, Gordon C S Smith

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Hsu Phern Chonga Department of Obstetrics and Gynecology , University of Cambridge, NIHR Cambridge Comprehensive Biomedical Research Centre , Cambridge , UK.
J Frederik Frøenb Department of International Public Health , Norwegian Institute of Public Health , Nydalen , Norway.
Sylvia Richardsonc MRC Biostatistics Unit , Cambridge Institute of Public Health , Cambridge , UK.
Benoit Liquetc MRC Biostatistics Unit , Cambridge Institute of Public Health , Cambridge , UK.
D Stephen Charnock-Jonesa Department of Obstetrics and Gynecology , University of Cambridge, NIHR Cambridge Comprehensive Biomedical Research Centre , Cambridge , UK.
Gordon C S Smitha Department of Obstetrics and Gynecology , University of Cambridge, NIHR Cambridge Comprehensive Biomedical Research Centre , Cambridge , UK.
University of Cambridge · GBMRC Biostatistics Unit · GBNorwegian Institute of Public Health · NO

Funding

Medical Research Council MC_UP_0801/1Medical Research Council MC_UU_00002/10
6 · The paper itself

Abstract

objectivesWe sought to evaluate the impact of later menarche on the risk of operative delivery. POPULATION: We studied 38,069 eligible women (first labors at term with a singleton infant in a cephalic presentation) from the Norwegian Mothers and Child Cohort Study. The main exposures were the age at menarche and the duration of the interval between menarche and the first birth.

methodsPoisson's regression with a robust variance estimator.

main outcome measuresOperative delivery, defined as emergency cesarean or assisted vaginal delivery (ventouse extraction or forceps).

resultsA 5 year increase in age at menarche was associated with a reduced risk of operative delivery (risk ratio [RR] 0.84, 95%CI 0.78, 0.89; p < .001). Adjustment for the age at first birth slightly strengthened the association (RR 0.79, 95%CI 0.74, 0.84; p < .001). However, the association was lost following adjustment for the menarche to birth interval (RR 0.99, 95%CI 0.93, 1.06; p = .81). A 5 years increase in menarche to birth interval was associated with an increased risk of operative delivery (RR 1.26, 95%CI 1.23, 1.28; p < .001). This was not materially affected by adjustment for an extensive series of maternal characteristics (RR 1.23, 95%CI 1.20, 1.25; p < .001).

conclusionsLater menarche reduces the risk of an operative first birth through shortening the menarche to birth interval. This observation is consistent with the hypothesis that the pattern and/or duration of prepregnancy exposure of the uterus to estrogen and progesterone contributes to uterine aging.

Indexed as

AdultAge FactorsCesarean SectionDelivery, ObstetricExtraction, ObstetricalFemaleHumansInfant, NewbornMaleMenarcheNorwayObstetrical ForcepsObstetric Labor ComplicationsPregnancyRisk FactorsTerm Birthcesareanmaternal ageMenarcheoperative vaginal delivery

Identifiers

PMID28958167
PMCPMC6181208
OpenAlexW2760361078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.