Evidence map›Paper›PMID 28958023›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2018

A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study.

Haiying Chen, W Jack Rejeski, Thomas M Gill, Jack Guralnik, Abby C King, Anne Newman, Steven N Blair, David Conroy, Christine Liu, Todd M Manini and 4 more

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. An Incomplete Model of Disability: Discrepancies Between Performance-Based and Self-Reported Measures of Functioning.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  3. Subjective Motoric Complaints and New Onset Slow Gait.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  4. Recovery From Mobility Limitation in Middle-Aged African Americans: The Jackson Heart Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Haiying ChenDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
W Jack RejeskiDepartment of Health and Exercise Science, Wake Forest University, Winston-Salem, North Carolina.
Thomas M GillDepartment of Internal Medicine/Geriatrics, Yale University, New Haven, Connecticut.
Jack GuralnikDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore.
Abby C KingHealth Research & Policy Department and Department of Medicine (Stanford Prevention Research Center), Stanford University School of Medicine, California.
Anne NewmanDepartment of Epidemiology, University of Pittsburgh, Pennsylvania.
Steven N BlairArnold School of Public Health, University of South Carolina, Columbia.
David ConroyDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois.
Christine LiuNutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer Human Nutrition Research Center in Aging, Tufts University, Boston, Massachusetts.
Todd M ManiniDepartment of Aging and Geriatric Research, University of Florida, Gainesville.
Marco PahorDepartment of Aging and Geriatric Research, University of Florida, Gainesville.
Walter T AmbrosiusDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Michael E MillerDepartment of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.
LIFE Study

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
6 · The paper itself

Abstract

Background: The objective assessment of major mobility disability (objective MMD) by a 400-m walk test (400 MWT) is important but not always practical. Previous research on the relationship between self-reported MMD (SR MMD) and objective MMD is sparse and limited to cross-sectional data. Methods: We evaluated agreement between SR MMD and objective MMD using longitudinal data from the Lifestyle Interventions for Elders (LIFE) study. The SR MMD indices were defined based on having a lot of difficulty or inability to walk a quarter of a mile (SR-1/4MILE), walk several blocks (SR-BLOCKS), and climb one flight of stairs (SR-STAIRS). Results: Using objective MMD as the gold standard, SR-1/4MILE and SR-BLOCKS had relatively low sensitivity (around 0.4) and high specificity (around 0.9) for prevalence. Their overall sensitivity and specificity for cumulative incident objective MMD were approximately 0.6 and 0.8, respectively. While the annual probability of staying MMD free was similar for objective MMD, SR-1/4MILE, and SR-BLOCKS (90% for all), the probability of recovering from SR MMD was higher (50%) than that of objective MMD (22%). The development of objective MMD (439 events), SR-1/4MILE (356 events), and SR-BLOCKS (379 events) had a similar trajectory over time with substantially overlapping survival curves. SR-STAIRS generally did not agree well with objective MMD. Incorporating SR-STAIRS with either SR-1/4MILE or SR-BLOCKS did not significantly improve the agreement between SR MMD and objective MMD. Conclusions: Simple SR-1/4MILE and SR-BLOCKS are reasonable candidates to define MMD if the primary outcome of interest is incident MMD.

Indexed as

Mobility LimitationSelf ReportWalk TestAgedAged, 80 and overDisability EvaluationFemaleHumansLongitudinal StudiesMaleSensitivity and SpecificitySingle-Blind Method

Identifiers

PMID28958023
PMCPMC5861858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.