Evidence map›Paper›PMID 28958000›Full record

Observational studyThe journals of gerontology. Series A, Biological sciences and medical sciences2018

Validation of Gait Characteristics Extracted From Raw Accelerometry During Walking Against Measures of Physical Function, Mobility, Fatigability, and Fitness.

Jacek K Urbanek, Vadim Zipunnikov, Tamara Harris, Ciprian Crainiceanu, Jaroslaw Harezlak, Nancy W Glynn

Abstract readObservational StudyValidation Study
In one paragraph

Observational study in The journals of gerontology. Series A, Biological sciences and medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Real-world walking and activity patterns in community-dwelling older adults: a cross-sectional analysis of baseline data from the SMART-AGE trial.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
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  14. Changes in Objectively Measured Physical Activity Are Associated With Perceived Physical and Mental Fatigability in Older Men.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  15. Article
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  17. Article
  18. Evaluation of the Bidirectional Relations of Perceived Physical Fatigability and Physical Activity on Slower Gait Speed.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  19. Variability in Hourly Activity Levels: Statistical Noise or Insight Into Older Adult Frailty?The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
  20. Response to "Comment on: Fatigability: A Prognostic Indicator of Phenotypic Aging".The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jacek K UrbanekDepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Vadim ZipunnikovDepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Tamara HarrisLaboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland.
Ciprian CrainiceanuDepartment of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.
Jaroslaw HarezlakDepartment of Epidemiology and Biostatistics, School of Public Health, Indiana University, Bloomington.
Nancy W GlynnDepartment of Epidemiology, Center for Aging and Population Health, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000181 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 1989 to 2025
$6.2M
Statistical methods for analyzing objectively measured physical activity dataR01HL130483 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Chongzhi Di · 2016 to 2026
$4.4M
Statistical Methods for Mapping Human Brain DevelopmentR01MH095836 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REISS, PHILIP T · 2012 to 2016
$2.1M
Statistical models for multi-modal brain imaging studies of HIV-associated cognitive declineR01MH108467 · NIMH · INDIANA UNIVERSITY INDIANAPOLIS · PI HAREZLAK, JAROSLAW · 2015 to 2019
$2.0M
Statistical methods for large and complex databases of ultra-high-dimensionalR01NS085211 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2013 to 2017
$1.8M
Statistical methods for biosignals with varying domainsR01HL123407 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CRAINICEANU, CIPRIAN M · 2014 to 2017
$1.6M
NHLBI NIH HHS R01 HL123407NHLBI NIH HHS R01 HL130483NIA NIH HHS P30 AG024827NIA NIH HHS T32 AG000181NIMH NIH HHS R01 MH095836NIMH NIH HHS R01 MH108467NINDS NIH HHS R01 NS085211
6 · The paper itself

Abstract

Background: Data collected by wearable accelerometry devices can be used to identify periods of sustained harmonic walking. This report aims to establish whether the features of walking identified in the laboratory and free-living environments are associated with each other as well as measures of physical function, mobility, fatigability, and fitness. Methods: Fifty-one older adults (mean age 78.31) enrolled in the Developmental Epidemiologic Cohort Study were included in the analyses. The study included an "in-the-lab" component as well as 7 days of monitoring "in-the-wild" (free living). Participants were equipped with hip-worn Actigraph GT3X+ activity monitors, which collect raw accelerometry data. We applied a walking identification algorithm and defined features of walking, including participant-specific walking acceleration and cadence. The association between these walking features and physical function, mobility, fatigability, and fitness was quantified using linear regression analysis. Results: Acceleration and cadence estimated from "in-the-lab" and "in-the-wild" data were significantly associated with each other (p < .05). However, walking acceleration "in-the-lab" was on average 96% higher than "in-the-wild," whereas cadence "in-the-lab" was on average 20% higher than "in-the-wild." Acceleration and cadence were associated with measures of physical function, mobility, fatigability, and fitness (p < .05) in both "in-the-lab" and "in-the-wild" settings. In addition, "in-the-wild" daily walking time was associated with fitness (p < .05). Conclusions: The quantitative difference in proposed walking features indicates that participants may overperform when observed "in-the-lab." Also, proposed features of walking were significantly associated with measures of physical function, mobility, fatigability, and fitness, which provides evidence of convergent validity.

Indexed as

AccelerometryAgedAlgorithmsCross-Sectional StudiesFatigueFemaleGaitGeriatric AssessmentHumansMaleMobility LimitationPhysical FitnessSedentary BehaviorWalking

Identifiers

PMID28958000
PMCPMC5905654

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.